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Khirurgii

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Year 2010 Vol. 18 No 6

GENERAL AND SPECIAL SURGERY

DOVNAR R.I., SMOTRIN S.M., VASIL’KOV A.YU., ZHMAKIN A.I.

ANTIBACTERIAL AND ANTIFUNGAL EFFECT OF THE BANDAGING MATERIAL CONTAINING SILVER NANOPARTICLES

Objectives. To study antibacterial and antifungal effect of the bandaging material on the basis of medical gauze bandage containing silver nanoparticles obtained by means of the metal vapor synthesis method.
Methods. In the research the strains of microorganisms and fungi of Candida genus were used which had been isolated from the purulent wounds of the surgical patients. Determination of the antibacterial and antifungal effect of the bandaging containing silver nanoparticles was performed on Petri dishes with agar. A usual medical gauze bandage was used for control. Sensitivity to antibiotics and antibacterial preparations had been previously revealed in these strains of microorganisms. The correlation analysis of antibacterial action of the bandaging containing silver nanoparticles was carried out as well as the analysis of microorganisms’ sensitivity to antibiotics.
Results. Medical gauze bandage containing silver nanoparticles was found out to have antibacterial and antifungal action. The performed correlation analysis showed that there was no any link between microbes’ resistance to antibiotics and resistance to silver nanoparticles.
Conclusions. Nanocomposite material silver/bandage has a marked antimicrobial action in relation to gram-positive and gram-negative bacteria and Candida. Microorganisms’ resistance to silver-containing bandaging doesn’t correlate with the range and level of their sensitivity to antibiotics.

Keywords: silver nanoparticles, antibacterial and antifungal effect, medical gauze bandage
p. 3 – 11 of the original issue
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