Year 2012 Vol. 20 No 4

UROLOGY

A.K. USOVICH, V.A. KRASNOBAEV

PECULIARITIES OF STRUCTURAL ORGANIZATION OF MUSCULAR TISSUE AND CONCREMENT FORMATION IN HUMAN PROSTATE

EE “Vitebsk State Medical University”
The Republic Of Belarus

Objectives. To reveal age-specific periods of the prostatic concrements definition and establish the interrelation of lithogenesis with prostate muscular tissue peculiarities.
Methods. 303 prostates of corpses from twenty-week fetuses up to ninety-three year old men who have died accidentally and lethality was not connected with genitourinary apparatus and pelvic organs pathology made up the research material.
Results. It has been established that in the period of human prostate development (fetuses - teenagers) when intensity of the prostate glands secretion is not high the prostatic concrements have not been found. At young men as a result of intensive growth of prostate gland and increase of their secretory activity on the background of lagging of the glandular muscular cover formation the prostatic concrements are formed.
In the period of the highest organ functional activity (22-35 years) the structure of muscular tissue is formed in human prostate providing a full evacuation of a secret from actively functioning prostatic glands. In the period of age prostate involution which morphological manifestations are revealed in some men from the age of 38 the total thinning of myocyte bundles is observed as well as the density reduction of their location around the terminal segments of prostatic glands. As a consequence of it the internal secretion of the prostate gland accelerates growth and diameter of concrements.
At the senile age in comparison with elderly one the specific volumes of muscular and elastic tissues decrease significantly as well as the thickness and myocytes density location. The expressed bundles of the smooth muscular tissue have not observed. Prostatic corpuscles have been found in the lumens of all glandular segments.
Conclusions. Concrements in the prostate have been found in young and older than 38 years persons. Presence of concrements is revealed in such sites of the prostate where the structure of the muscular bundles cannot provide a full secret evacuation from the glands.

Keywords: muscular tissue, prostate, concrements
p. 81 – 86 of the original issue
References

1. Liul'ko AV, Pytel', red. Zabolevaniia predstatel'noi zhelezy [Prostate disease]. Kiev, SSSR: Zdorov’ia, 1984. 280 p.
2. Arnol'di EK. Khronicheskii prostatit [Chronic prostatitis]. Rostov n/Donu, SSSR: Feniks, 1999. 234 p.
3. Pomerantsev AA. Mnogotomnoe rukovodstvo po khirurgii: v 9 t. [Multi-volume manual of surgery: in 9 v.]. Moscow, RF: Medgiz, 1959. T.9: Kamni predstatel'noi zhelezy. p. 417–20.
4. Mavrov II. Polovye bolezni: Entsiklopedicheskii spravochnik [Sexual disease: an encyclopedic reference book]. Kiev, Moscow, SSSR: 1994. 480 p.
5.Yanamandra K, Alexeyev O, Zamotin V, Srivastava V, Shchukarev A, Brorsson AC, Tartaglia GG, Vogl T, Kayed R, Wingsle G, Olsson J, Dobson CM, Bergh A, Elgh F, Morozova-Roche LA. Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate. PLoS One. 2009;4(5):e5562.
6. Dikov D, Staribratova D, Belovejdov V. Corpora amylacea in prostatic stromal smooth muscle cells. Indian J Pathol Microbiol. 2010 Jul-Sep;53(3):584–85.
7. Untergasser G, Madersbacher S, Berger P. Benign prostatic hyperplasia: age-related tissue-remodeling. Exp Gerontol. 2005 Mar;40(3):121–28.
8. De Marzo AM, Platz EA, Sutcliffe S, Xu J, Gronberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG. Inflammation in prostate carcinogenesis. Nat Rev Cancer. 2007 Apr;7(4):256–69.
9. Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002 Dec 19-26;420(6917):860–67.
10. Molochkov VA, Il'in II, Molochkov VA. Khronicheskii uretrogennyi prostatit [Chronic uretrogenic prostatitis ]. Ìoscow, RF: Meditsina, 1998. 304 p.
11. Gorpinchenko II, Proshchiko KV, Pedchenko OIa. O kamneobrazovanii v predstatel'noi zheleze pri khronicheskim prostatite [The stone formation in the prostate in chronic prostatitis]. Vracheb Delo. 1992;(11–12):93–96.
12. Bunak VV. Vydelenie etapov ontogeneza i khronologicheskie granitsy vozrastnykh periodov [Isolation of stages of ontogenesis and chronological boundaries of age periods]. Sovetskaia pedagogika. 1965;(11):105–06.
13. Avtandilov GG. Meditsinskaia morfometriia. Rukovodstvo [Medical morphometry. A guide]. Moscow, SSSR: Meditsina, 1990. 384 p.

Address for correspondence:
210023, Respublika Belarus, Vitebsk, pr. Frunze, d. 27, UO «Vitebskiy gosudarstvennyiy meditsinskiy universitet», kafedra anatomii cheloveka,
e-mail: krasnobayev@bk.ru,
Krasnobaev Vladimir Alekseevich
Information about the authors:
Usovich A.K., Doctor of Medical Sciences, Head of the Human Anatomy Chair of EE “Vitebsk State Medical University”
Krasnobaev V.A., Assistant, Extramural Post-Graduate of the Human Anatomy Chair of EE “Vitebsk State Medical University”
Contacts | ©Vitebsk State Medical University, 2007-2023