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Year 2011 Vol. 19 No 2

GENERAL AND SPECIAL SURGERY

KUGAEV M.I., SCHASTNY A.T., SAMSONOVA I.V.

RELATIONSHIP OF THE PATHOMORPHOLOGICAL CHANGES IN THE PANCREATIC HEAD WITH PAIN SYNDROME INTEN INTENSITY

Objectives. To investigate the relationship between the indicators of quality of life, severity of pain and morphological changes in the pancreas (P) in chronic pancreatitis (CP)
Methods. 51 patients were examined. To evaluate the intensity of pain the visual analogue scale (VAS was used); to examine the quality of life (QOL) questionnaire SF-36 was used. Material for microscopic examination was taken during the resection of the pancreas head.
Results. A wide range of fibrotic changes in the pancreas head was revealed. The correlation between the intensity of pain, QOL and an area of fibrosis wasn’t found. When comparing groups of patients with pancreatic head size of less than 40 mm and more than 40 mm, the area of fibrosis was not significantly different. When comparing groups of patients with the width of the main pancreatic duct (MPD) of less than 6 mm and more than 6 mm, the area of fibrosis was not significantly different.
Conclusions. QOL and intensity of pain don’t correlate with the degree of fibrotic changes occurring in the pancreas head. Pancreatic head size and width of the main pancreatic duct don’t depend on the degree of fibrotic changes in the pancreas head.

Keywords: chronic pancreatitis, fibrosis of the pancreas, the quality of life, intensity of pain, the width of the main pancreatic duct, the size of the pancreatic head
p. 31 – 36 of the original issue
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