Novosti
Khirurgii

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Year 2021 Vol. 29 No 2

CASE REPORTS

T.V.KOZLOVA, Ì.S. MATVIEIENKO, I.V. BELOZOROV, E.YA. NIKOLENKO

PULMONARY EMBOLISM IN POLYTRAUMA: DIAGNOSIS AND TREATMENT

V.N. Karazin Kharkov National University, Kharkov,
Ukraine

Treatment of patients with polytrauma is a difficult problem for surgeons and physicians of intensive care units due to the fact that a multiple and complex lesion often serves as a trigger for the development of a number of life-threatening complications, such as pulmonary embolism (PE). Despite the existing methods of prevention and treatment of pulmonary embolism, the development of this complication in patients with polytrauma accompanied by massive hemorrhage is still remains an unsolved problem. This article presents a clinical case of the development of isolated PE during performing osteosynthesis of the patient with polytrauma and in stable condition achieved after the intensive therapy within the week. The analize of studies considering the problem of thrombus formation in various parts of the vascular bed and considering of pathophysioliogycal mechanisms of the systemic inflammatory response has been performed. Risk factors for pulmonary embolism and methods of prophylaxis are studied. Taking into consideration the currently available research data dedicated to this issue, the idea about the generalized nature of the pathological process which can be manifested as deep vein thrombosis such as PE or their combination has been expressed. In respect the insufficient effectiveness of thromboprophylaxis, the need to work out the other or additional laboratory and diagnostic methods of blood coagulation system assessment and responsively therapeutic methods is being considered.

Keywords: polytrauma, pulmonary embolism, thrombosis, systemic vascular reaction, inflammation, coagulation
p. 242-249 of the original issue
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Address for correspondence:
61022, Ukraine, Kharkov,
Svoboda Square, 6,
V.N. Karazin Kharkov National University,
the Department of Surgical Diseases,
Operative Surgery and Topographic Anatomy
tel.: +38-050-161-98-36
E-mail: mariia.matvieienko@karazin.ua
Matvieienko Mariia S.
Information about the authors:
Kozlova Tatiana V., MD. Associate Professor, the Department of General and Clinical Pathology. V.N. Karazin Kharkov National University, Kharkov, Ukraine.
https://orcid.org/0000-0003-0432-6967
Matvieienko Mariia S., Assistant of the Department of Surgical Diseases, Operative Surgery and Topographic Anatomy, V.N. Karazin Kharkov National University, Kharkov, Ukraine.
http://orcid.org/0000-0002-0388-138X
Belozorov Igor V., MD, Professor of the Department of Surgical Diseases, Operative Surgery and Topographic Anatomy, V.N. Karazin Kharkov National University, Kharkov, Ukraine.
https://orcid.org/0000-0002-4102-3220
Nikolenko Evgene Y., MD, Professor of the Department of General Practice and Family Medicine, V.N. Karazin Kharkov National University, Kharkov, Ukraine.
https://orcid.org/0000-0002-7653-0644
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