Year 2012 Vol. 20 No 1

EXPERIMENTAL SURGERY

V.A. NOVOSELETSKY 1, O.G. KHOROV 1, V.A. STRUK 2

INFLUENCE ANALYSIS OF ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE OF HIGH DENSITY ON SOME BIOCHEMICAL BLOOD PARAMETERS IN EXPERIMENT

EE “Grodno State Medical University” 1,
EE “Grodno State University named after Yanka Kupala” 2,
The Republic of Belarus

Objectives. To evaluate the influence of the material from the modified ultra-high molecular weight polyethylene of high density (UHMWPE) at its implantation in the ear bulla of a rabbit on some biochemical blood parameters in comparison with titanium, which is widely applied in otosurgery.
Methods. 35 rabbits were used to carry out the experiment; they were divided into 3 groups. The 1st as well as the 2nd group included 15 animals which were excluded from the experiment 15, 60 and 90 days afterwards (5 animals in each term); the 3rd group was a control one (5 rabbits). In the 1st group implants from the modified ultra-high molecular weight polyethylene were used; in the 2nd group – from titanium; the 3rd group wasn’t operated on at all.
Results. While comparing two experimental groups of animals with the control group reliable differences in the blood content of bilirubin, AST, glucose, creatinine, total protein in different terms after operation were not revealed.
Conclusions. UHMWPE can be regarded as a material suitable for further investigations aimed to work out the original domestic construction of prosthesis of the ossicular chain.

Keywords: ultra-high molecular weight polyethylene of high density, ossiculoplasty, prosthesis
p. 20 – 24 of the original issue
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Address for correspondence:
230009, Respublika Belarus', g. Grodno, ul. Gor'kogo, d. 80, UO “Grodnenskii gosudarstvennyi meditsinskii universitet”, kafedra otorinolaringologii i stomatologii,
e-mail: novasialetski@rambler.ru,
Novoseletskii Vladimir Aleksandrovich
Information about the authors:
Novoseletsky V.A. Lecturer of the military chair of EE “Grodno State Medical University”.
Khorov O.G. Doctor of medical sciences, professor, head of otolaryngology, dentistry chair of EE “Grodno State Medical University.
Struk V.A. Doctor of technical sciences, professor, dean of the faculty of the innovative technologies of the machine-building of EE “Grodno State University named after Yanka Kupala”.
Novoseletsky V.A. Lecturer of the military chair of EE “Grodno State Medical University”.
Khorov O.G. Doctor of medical sciences, professor, head of otolaryngology, dentistry chair of EE “Grodno State Medical University.
Struk V.A. Doctor of technical sciences, professor, dean of the faculty of the innovative technologies of the machine-building of EE “Grodno State University named after Yanka Kupala”.
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