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Year 2020 Vol. 28 No 5

CASE REPORTS

I. VYNNYCHENKO 1, M. KONONENKO 1, O. SMORODSKA 1, 2, S. IVANOV 2, Y. MOSKALENKO 1, O. VYNNYCHENKO 1, V. SIKORA 1, M. LYNDIN 1, A. ROMANIUK 1

CASE REPORT OF GIANT NONMETASTATIC GASTROINTESTINAL SOLID TUMOR WITHOUT CLINICAL MANIFESTATIONS IN A MIDDLE-AGED MALE PATIENT

Sumy State University 1,
Utility Non-Profit Enterprise Clinical Hospital No5 of Sumy Municipal Council 2, Sumy,
Ukraine

Gastrointestinal stromal tumors (GIST) are one of the most common mesenchymal tumors that originate from the intestinal cells of Cajal. The most common localization of GIST is the gastrointestinal tract, however, extragastrointestinal forms are sometimes found. Most GISTs are small in size, which most often does not exceed 5 - 8 cm in maximum dimension. This article describes the case of a patient with a non-metastatic giant tumor of the stomach without any clinical manifestations. The tumor was localized in the abdominal cavity, occupying almost all of it, squeezing and displacing the surrounding organs. Due to the cystic-solid structure, its gigantic size and intimate adherence to the surrounding organs, it was not possible to carry out an accurate differential diagnosis before surgery. Intraoperative imaging of the tumor, further histological and immunohistochemical (CD117, CD34, S100, CD45, PanCK; Ki-67) studies made possible to establish the diagnosis of gastric GIST T4N0M0 stage II. Based on the data obtained, despite the gigantic size, the prognosis of the disease was considered favorable (low mitotic index, no metastasis). During the period of clinical observation, within 1.5 years after surgery, no relapse or disease progression was recorded, which indicates a favorable prognosis for the patient.

Keywords: gastric tumor, gastrointestinal stromal tumor, giant tumor, operative treatment
p. 597-602 of the original issue
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Address for correspondence:
40022, Ukraine,
Sumy, Privokzalnaya str., 31,
Medical Institute of Sumy State
Medical University, the Department
of Oncology and Radiology,
tel.: +38 095 8 000 489,
e-mail: smorodska1991@gmail.com,
Smorodska Olga N.
Information about the authors:
Vynnychenko Ihor A., PhD, Associate Professor, Head of the Department of Oncology and Radiology, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0002-2339-6509
Kononenko Mykola G., MD, Professor of the Surgery Department, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0003-3068-1751
Smorodska Olga N., Post-Graduate Student of the Department of Oncology and Radiology, Medical Institute of Sumy State Medical University, Surgeon, Clinical Hospital No5, Sumy, Ukraine.
http://orcid.org/0000-0002-9028-3379
Ivanov StanislavS., Surgeon, Clinical Hospital No5, Sumy, Ukraine.
http://orcid.org/0000-0001-8897-0041
MoskalenkoYuliia V., PhD, Assistant of the Department of Oncology and Radiology, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0002-5398-0298
Vynnychenko Oleksandr I., PhD, Assistant of the Department of Oncology and Radiology, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0001-5651-0323
Sikora Vladyslav V., PhD, Assistant of the Pathologic Anatomy Department, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0002-4147-6879
Lyndin Mykola S., PhD, Assistant of the Pathologic Anatomy Department, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0003-4385-3903
Romaniuk Anatolii N., MD, Professor, Head of the Pathologic Anatomy Department, Medical Institute of Sumy State Medical University, Sumy, Ukraine.
http://orcid.org/0000-0003-2560-1382
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