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Khirurgii

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Year 2023 Vol. 31 No 2

SCIENTIFIC PUBLICATIONS

S.P. DOSMAGAMBETOV 1, B.K. DZHENALAEV 1, G.D. ZHUMAGALIYEVA 1, A.B. TUSSUPKALIEV 1, B.N. BISSALIYEV 1, G.Z. ABDULLAEVA 2

DIFFERENTIAL DIAGNOSIS OF ACUTE APPENDICITIS IN CHILDREN WITH COVID-19 ASSOCIATED MULTISYSTEM INFLAMMATORY SYNDROME

West Kazakhstan Medical University named after Marat Ospanov 1,
Motherhood and Childhood Care Center 2, Aktobe,
Republic of Kazakhstan

The publication describes clinical observations of children with multisystem inflammatory syndrome (MSIS) associated with SARS-CoV-2. The difficulties of diagnosis and differential diagnosis with acute appendicitis, peritonitis are shown. In April 2020, in the UK, there were reports of children having a picture of the disease similar to incomplete Kawasaki syndrome or toxic shock syndrome. Many researchers have concluded that MSVS is a dangerous systemic infectious disease characterized by extreme inflammation, fever, abdominal symptoms, conjunctivitis, and rash.
It is believed that the cause of abdominal pain in MSIS is mesenteric lymphadenitis, serous peritonitis. Ignorance of the manifestations of MSVS in children leads to late diagnosis of this severe pathology and futile surgical intervention.
Currently, many publications have appeared describing MSIS associated with SARS-CoV-2. WHO has developed a preliminary case definition and a case report form for multisystem inflammatory syndrome in children and adolescents. The preliminary case determination reflects the clinical and laboratory features observed in children that have been reported to date, and serves to identify suspected or confirmed cases, both for the purpose of providing treatment, and for preliminary reporting and follow-up. Therefore, there is an urgent need to collect standardized data describing clinical manifestations, severity, outcomes, and epidemiology.
During the current pandemic, paediatric surgeons should be more alert to MSIS when treating children with fever and acute abdomen. Early diagnosis of MSIS will allow you to avoid unnecessary operations that can worsen the already serious condition of the patient.
Taking into account the difficulties in the differential diagnosis of MSIS with acute surgical pathology of the abdominal cavity, it is important to ensure a multidisciplinary approach in the timely diagnosis of MSIS in seriously ill children. Only a joint examination of such specialists as an infectious disease specialist, cardiologist, pulmonologist, hematologist, nephrologist, pediatrician, pediatric surgeon and laboratory tests (clinical blood test, C-reactive protein, D-dimer, coagulogram), echocardiography, CT will allow timely detection of MSIS in children, to exclude surgical pathology of the abdominal cavity.

Keywords: multisystem inflammatory syndrome, acute appendicitis, peritonitis, mesadenitis, multidisciplinary approach
p. 127-136 of the original issue
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Address for correspondence:
030019, the Republic of Kazakhstan,
Aktobe, Maresyev st., 68,
West Kazakhstan Medical University
Named after Marat Ospanov,
Department of Pediatric Surgery,
Tel. +7 701 559-68-10,
e-mail: Dossag2011@mail.ru,
Dosmagambetov Sagidulla P.
Information about the authors:
Dosmagambetov Sagidulla P., Candidate of medical sciences (PhD), associate professor of the chair of pediatric surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan.
http://orcid.org/0000-0002-6525-8438
Dzhenalaev Bulat K., Doctor of medical sciences (PhD, MD), professor of the chair of pediatric surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan.
http://orcid.org/0000-0001-7494-5072
Zhumagaliyeva Galina D., Candidate of medical sciences (PhD), associate professor of the course of infectious diseases in children, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan.
http://orcid.org/0000-0002-5448-072X
Tussupkaliev Assylbek B., Candidate of medical sciences (PhD), associate professor of the chair of pediatric surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan.
http://orcid.org/0000-0003-2386-2984
Bissaliyev Bauyrzhan N., Candidate of medical sciences (PhD), associate professor of the chair of pediatric surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan. http://orcid.org/0000-0002-4875-1140
Abdullaeva Gulzhamal Z., Head of the Intensive Care Unit of the pediatric in-patient department of Aktyubinsk Medical Centre, Aktobe, Republic of Kazakhstan.
http://orcid.org/0000-0002-9018-5891
Contacts | ©Vitebsk State Medical University, 2007-2023