Novosti
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This journal is indexed in Scopus |
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Year 2010 Vol. 18 No 6
ANESTHESIOLOGY-REANIMATOLOGY
KANUS I.I., GRACHEV S.S.
COMPARATIVE CHARACTERISTICS OF ARDUAN, ARCURON AND ESMERON ACTION PARAMETERS AT INTRAABDOMINAL SURGICAL INTERVENTIONS
Objectives. To perform the comparative investigation of the neuromuscular blocking non-depolarizing type agents’ actions at abdominal surgeries.
Methods. 130 patients, at the age of 17 to 78 (ASA I-IV) with a surgical abdominal pathology were included in the investigation. All patients were divided into 3 groups depending on the neuromuscular blocking agent use: the 1st group – 45 patients in whom arduan was used; the 2nd group – 42 patients in whom arcuron was used; the 3rd group – 43 patients in whom esmeron was used.
Results. It is established, that in case of a single or repeated esmeron application, action duration is shorter than similar action parameters of arduan and arcuron for 42–45%. It is proved, that precuraresation reduces the time of all agents in study action start for 0,5–1,0 min. Clinical duration of action, t-90 period, total myoplegia time were increased after precurarezation for 15–22,3%. The data were obtained that succinylcholine decreased arduan, arcuron and esmeron recovery period duration in case of a single or repeated application
Conclusions. Esmeron has the optimal characteristics ensuring the neuromuscular block’s obtainment, maintenance and reversion during an abdominal surgery.
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