Year 2021 Vol. 29 No 3

UROLOGY

S.I. PANIN, A.V. BYKOV, A.B. DORONIN, A.A. KUZNETSOV, S.V. SHCHELKOV, A.A. PANINA, E.A. MOROZOV, S.N. KARPENKO

EVALUATION OF TREATMENT RESULTS OF UROLITHIASIS COMPLICATIONS AMONG COVID-19 PATIENTS

Volgograd State Medical University, Volgograd,
The Russian Federation

Objective. To study the peculiarities of diagnostics and treatment of urolithiasis complications among patients with new coronavirus infection COVID-19.
Methods. The prospective cohort study evaluated the treatment outcomes of patients (n=146). The first group (n=30) included patients treated in infectious diseases hospital with a complicated urinary calculi disease and a new coronavirus infection COVID-19, the second group (n=116) included patients treated in the urological department of multidisciplinary non-infectious hospital due to complicated urinary tract stone disease who were not infected by new coronavirus infection COVID-19. As for COVID 19 diagnostics, patients of the first group were done PCR tests that were positive in 19 (63,3%) cases, and thoracic cavity computer tomography scanning (upon admission the percentage of pulmonary tissue involvement varied since 5% up to 90%).
Results. Among the patients of the first group, elderly people prevailed (61+15 years) and there were more women among them (66%). The characteristic features of complicated urinary calculi disease in patients with COVID-19 are the prevalence of infectious and inflammatory complications (50%) and a combination of several complications of urolithiasis (40%). Among peculiarities of treatment, patients of the first group in 6.6% of cases underwent the lumbotomy with open nephrostomy, due to the spread of secondary suppurative process over the retroperitoneal space. According to the Clavien-Dindo scale, in the first group of patients the incidence of complications after surgery was 40%, in the second - 13.8%. Mortality rate in the first group reached 30%, in the second 0.9%. The duration of hospital treatment among patients of the first group reached 21 (5-39) days, among patients of the second group 8 (1-56) days.
Conclusion. The specificity of the course associated with significant morbidity and mortality require further optimization therapeutic approaches to achieve success in patients with complications of urolithiasis during COVID-19 outbreak.

Keywords: complications of urolithiasis, lumbotomy, urinary tract drainage, mortality rate, COVID-19
p. 318-326 of the original issue
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Address for correspondence:
400131, Russian Federation,
Volgograd, Pavshie Bortsy Square, 1
Volgograd State Medical University,
the Department of the General Surgery
with the Course Of Urology,
tel. +7 903 375-57-95,
e-mail: kouznetsov23@gmail.com,
Kuznetsov Alexandr A.
Information about the authors:
Panin Stanislav I., MD, Associate Professor, Head of the Department of the General Surgery with the Course of Urology, Volgograd State Medical University, Volgograd, Russian Federation.
https://orcid.org/0000-0003-4086-2054
Bykov Alexandr V., MD, Professor of the Department of Surgical Diseases No 1 of Institute of Continuing Medical and Pharmaceutical Education, Volgograd State Medical University, Volgograd, Russian Federation.
https://orcid.org/0000-0002-1505-6256
Doronin Andrey B., PhD, Associate Professor of the Department of the General Surgery with the Course of Urology, Volgograd State Medical University, Volgograd, Russian Federation.
https://orcid.org/0000-0003-2944-6762
Kuznetsov Alexandr A., PhD, Associate Professor of the Department of the General Surgery with the Course of Urology, Volgograd State Medical University, Volgograd, Russian Federation.
https://orcid.org/0000-0002-7026-1746
Shchelkov Sergey V., PhD, Associate Professor of the Department of Surgical Diseases No1 of Institute of Continuing Medical and Pharmaceutical Education, Volgograd State Medical University, Volgograd, Russian Federation.
https://orcid.org/0000-0001-8582-3687
Panina Anna A., PhD, Associate Professor of the Department of Radiation, Functional and Laboratory Diagnostics of Institute of Continuing Medical and Pharmaceutical Education, Volgograd State Medical University, Volgograd, Russian Federation.
http://orcid.org/0000-0003-2750-8579
Morozov Egor A., Assistant of the Department of the General Surgery with the Course of Urology, Volgograd State Medical University, Volgograd, Russian Federation.
http://orcid.org/0000-0001-9495-3424
Karpenko Svetlana N., PhD, Associate Professor of the Department of the General Surgery with the Course of Urology, Volgograd State Medical University, Volgograd, Russian Federation.
http://orcid.org/0000-0002-9965-392X
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