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Khirurgii

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Year 2015 Vol. 23 No 1

EXPERIMENTAL SURGERY

A.S. ZHIDKOV, V.E. KORIK, A.P.TRUKHAN, S.A. ZHIDKOV, S.N. PIVOVARCHIK, D.G. TERESHKO

DIRECT OXIMETRY IN DIAGNOSIS OF EXPERIMENTAL CRUSH SYNDROME

EE "Belarusian State Medical University"
The Republic of Belarus

Objectives. To study the changes in parameters of the direct oximetry of injured limb muscles, to determine their significance in diagnosis of crush syndrome (CD) and its severity in early postcompression period.
Methods. Guinea pigs (60 animals) were research models. Modeling of crush syndrome was carried out by application of the developed device of adjustable compression. The parameters of direct oximetry of the injured limbs muscles have been analyzed: oxygen partial pressure in muscles, oxygen mass transfer rates and oxygenation rate.
Results. Significant differences in comparing of oxygen mass transfer rate in the range of 150-155 mm Hg (V1) have been revealed between animals of the control group separately with each one of the comparison groups, which indicates some tissue respiration changes at any degree of crush syndrome. Within the first 48 hours in the group of animals with mild crush syndrome the increase of the indicator V1 was observed and with a moderate decline – on the third day. Analysis of data obtained in the group of animals with a moderate degree of pathological changes found no significant changes of the V1 indicator dynamics, while the analysis of the data obtained in the group of animals with severe pathology, showed a statistically significant permanent increase of oxygen mass transfer rate in the range of 150-155 mm Hg. In analyzing the oxygenation indicator the statistically significant differences have been revealed while comparing groups with mild, moderate and severe degrees of compression damage clearly differentiated a mild degree of pathological changes.
Conclusion. The method of direct oximetry permits to detect tissue hypoxia with compression injuries of the limbs, to differentiate mild and severe damages, as well as to predict the severe pathology in the early postcompression period.

Keywords: ñompression, crush syndrome, trauma, oximetry, rhabdomyolysis
p. 12-16 of the original issue
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Address for correspondence:
Respublika Belarus, g. Minsk,
ul. Engelsa d. 27,
UO "Belorusskiy gosudarstvennyiy
meditsinskiy universitet",
kafedra voenno-polevoy khirurgii;
tel.:+ 375 17 392-29-16;
E-mail: orcinus84@gmail.com;
Zhidkov Aleksey Sergeevich
Information about the authors:
Zhidkov A.S. An adjunct of military-field surgery chair of the military medical faculty of EE "Belarusian State Medical University".
Korik V.E. An adjunct of military-field surgery chair of the military medical faculty of EE "Belarusian State Medical University".
Zhidkov S.A. MD, professor of military-field surgery chair of the military medical faculty of EE "Belarusian State Medical University".
Trukhan A.P. PhD, associate professor of military-field surgery chair of the military medical faculty of EE "Belarusian State Medical University".
Pivovarchik S.N. A six-year student of the military medical faculty of EE "Belarusian State Medical University".
Tereshko D.G. A surgeon of the emergency and polyclinic department of the medical company.
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