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Year 2014 Vol. 22 No 2


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EE Vitebsk State Medical University
The Republic of Belarus

Objectives. To study the correlation of different levels of intraabdominal pressure with indicators of the respiratory index (PaO2/FiO2), PaCO2, the acid-base balance and necessity for carrying out a mechanical ventilation of the lungs (MVL) in patients with the acute destructive pancreatitis at hospitalization to the intensive care unit.
Methods. 70 patients with the acute destructive pancreatitis after transferring to the intensive care unit of a hospital have been examined. The indicators of intraabdominal pressure, the acid-base balance, PaCO2, a respiratory index and number of the patients demanded the mechanical lung ventilation onduction have been determined. Depending on the intraabdominal pressure level the patients were distributed into 3 groups. The received results were compared between the groups and their correlation was analyzed.
Results. At intraabdominal pressure up to 12 mm Hg the respiratory index and PaCO2 didnt change, thus 24% of patients demanded mechanical lung vantilation. Intraabdominal pressure over 12 mm Hg promoted the reduction of the respiratory index up to 236 mm Hg, thus 68 % of patients required MLV. Intraabdominal pressure over 20 mm Hg led to the reduction of the respiratory index up to 201 mm Hg and the increase 2, thus 100 % of patients required MLV. Indicators of the acid-base balance at different level of intraabdominal pressure (5-25 mm Hg) didnt change.
Conclusions. Intraabdominal pressure increase over 20 mm Hg in patients with the acute destructive pancreatitis leads to the respiratory insufficiency development and increase the number of the patients with MLV up to 100 %.

Keywords: acute destructive pancreatitis, respiratory insufficiency, intraabdominal pressure, respiratory index, acid-base balances
p. 213 217 of the original issue
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Address for correspondence:
210023, Respublika Belarus', g. Vitebsk, pr. Frunze, d. 27, UO Vitebskii gosudarstvennyi meditsinskii universitet, kafedra anesteziologii i reanimatologii s kursom FPK i PK,
Nikitina Ekaterina Vladimirovna
Information about the authors:
Nikitina E.V. PhD, an assistant of the anesthesiology and reanimatology chair with the course of advanced training and retraining of EE Vitebsk State Medical University.
Samsonova I.M. An assistant of the anesthesiology and reanimatology chair with the course of advanced training and retraining of EE Vitebsk State Medical University.
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