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Khirurgii

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Year 2013 Vol. 21 No 3

TRANSPLANTOLOGY

A.F. MINOU, A.M. DZYADZKO, A.E. SHCHERBA, O.O. RUMO

INFLUENCE OF THE TACTICS OF INTENSIVE THERAPY OF HEMOSTATIC DISORDERS ON INTRAOPERATIVE BLOOD TRANSFUSION REQUIREMENTS AND COURSE OF POSTOPERATIVE PERIOD FOLLOWING LIVER TRANSPLANTATION

RSPC "Transplantation of Organs and Tissues",
EHP "The 9th City Clinical hospital of Minsk"
The Republic of Belarus

Objectives. To compare the efficiency of intensive therapy of hemostatic disorders based on thromboelastometric data with the efficiency of intensive therapy of hemostatic disorders according to standard coagulation tests results.
Methods. 70 patients who underwent liver transplantation were enrolled in the study. Patients were randomized into two groups. The study group comprised of 35 patients to whom hemostatic abnormalities were corrected according to the thromboelastometric data, the control group comprised of 35 patients to whom hemostatic abnormalities were corrected according to standard coagulation tests results.
Results. Intensive therapy of hemorrhagic syndrome based on thromboelastometric data permits to reduce the blood loss from 1800 (1300-2000) ml to 1200 (1000-1700) ml and the amount of transfusions of RBCand FFP from 1447 (920-2120) ml and 2600 (2000-3400) ml to 1056 (692-1286) ml and 500 (0-1200) ml, respectively. Reduction of blood transfusions has led to decrease of the incidence of acute kidney injuries (from 88,6% to 65,7%) and shortening of the length of stay in intensive care units (from 6 to 5 days) and in the hospital (from 18 to 16 days).
Conclusions. The study confirmed the high efficiency of intensive therapy of hemostasis disorders based on thromboelastometric data compared with intensive therapy of hemostasis disorders based on the results of standard coagulation tests.

Keywords: liver transplantation, blood loss, thromboelastometrys
p. 69 – 78 of the original issue
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Address for correspondence:
220116, Respublika Belarus', g. Minsk, ul. Semashko, d. 8, UZ "9-ia Gorodskaia klinicheskaia bol'nitsa g. Minska", RNPTs Transplantatsii organov i tkanei, otdelenie anesteziologii,
e-mail: andrei.minou@gmail.com,
Minov Andrei Fedorovich
Information about the authors:
Minou A.F. A head of the anesthesiology and resuscitation department of RSPC “Transplantation of organs and tissues”, ME “The 9th Minsk city clinical hospital”.
Dzyadzko A.M. PhD, a head of the anesthesiology and resuscitation department of RSPC “Transplantation of organs and tissues”, ME “The 9th Minsk city clinical hospital”.
Shcherba A.E. PhD, a head of the transplantation department of RSPC “Transplantation of organs and tissues”, ME “The 9th Minsk city clinical hospital”.
Rumo O.O. MD, a head of RSPC “Transplantation of organs and tissues”, deputy chief physician on surgery of ME “The 9th Minsk city clinical hospital”.
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