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Year 2012 Vol. 20 No 4




EE Belarusian State Medical University 1 Minsk
Military Medical Administration of the Ministry of Defence of the Republic of Belarus2
The Republic of Belarus

Objectives. To study the impact of carbon dioxide and synthetic air insufflated to the abdominal cavity on the respiratory activity of the abdominal cavity organs of patients undergoing laparoscopic cholecystectomy.
Methods. Two groups of patients (62 patients in each group) with calculous cholecystitis were included in the investigation. To create a working space for the laparoscopic procedures in the first group carbon dioxide was used; in the second synthetic air. Investigation of the influence of gases on the internal organs oxygenation (liver, peritoneum and small intestine) was studied by the direct oximetry at the beginning of the operation (after setting the ports), insufflation of gas at the end of surgery prior to the removal of the tools.
Results. On insufflation of carbon dioxide the oxygen utilization rate by the peritoneum increased from 198,5 to 264,9 mm Hg/min, at the same time the oxygen content in it 2 times decreased from 125,4 to 64,2 mm Hg. The tissue respiration rate in the intestinal wall increased from 347,3 to 549,5 mm Hg/min and oxygen partial pressure increased from 121,9 to 144,7 mm Hg. The tissue respiration rate in the liver decreased from 215,8 to 73,4 mm Hg/min, and oxygen partial pressure increased from 74,3 to 132,3 mm Hg. While using the air gaseous mixture, statistically significant differences between the findings obtained at the beginning and at the end of the operation were not revealed.
Conclusions. The obtained data suggest that the peritoneum is easily permeable both to carbon dioxide and oxygen; in consequence of this the use of carbon dioxide markedly inhibits the oxygenation of the border tissue and causes acidemia. The air gaseous mixture has no significant effect on the respiratory activity of the organs and tissues.

Keywords: laparoscopy, cholecystectomy, oximetry, oxygenation
p. 29 -37 of the original issue

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Address for correspondence:
220034, Respublika BelarusMinsk, ul. Azgura, d. 4, UO Belorusskiy gosudarstvennyiy meditsinskiy universitet, voenno-meditsinskiy fakultetkafedra voenno-polevoy hirurgii
Klyuyko Dmitriy Aleksandrovich
Information about the authors:
Korik V.E., Candidate of Medical Sciences, Associate Professor, Colonel of Medical Service, Head of Military Field Surgery Chair of the Military Medicine Faculty of EE "Belarusian State Medical University."
Zhidkov S.A., Doctor of Medical Sciences, Professor, Colonel of Medical Service, the Chief of Military Medical Department of the Ministry of Defense of the Republic of Belarus
Klyuyko D.A., Major of Medical Service, Graduate Student of The Chair of MilitaryField Surgery of the Military Medicine Faculty of EE "Belarusian State Medical University."
Contacts | ©Vitebsk State Medical University, 2007