Novosti
Khirurgii
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Year 2008 Vol. 16 No 4

NEUROSURGERY

KUBRAKOV K.M., KOSINETS A.N., AKULENOK A.V.

INTRATHECAL INTRODUCTION OF ANTIBACTERIAL PREPARATIONS IN THE NEUROSURGERY PATIENTS WITH MENINGOENCEPHALITIS

The review of the modern literature is presented in the article concerning the methods and ways of the antimicrobial preparations administration in the neurosurgery patients with intracranial pyo-inflammatory complications. A preferable way of antibiotics administration is intravenous one. Intrathecal injection of antimicrobial preparation is also used in neurosurgery. However in literature there are no clearly motivated data for indication of antimicrobial preparation by this way. The statistical reliable criteria are chosen for the intrathecal administration the antimicrobial preparation by using the short-term prognosis model of lethal outcomes in the patients with postoperative meningoencephalitis. The model includes some findings of the blood (amount of leukocytes, lymphocytes, neutrophiles, and erythrocyte sedimentation rate), cerebrospinal fluid (the quantitative content of protein, relative content of neutrophiles and lymphocytes), presence of the traumatic brain injury of heavy degree, ischemic heart disease.

Keywords: neurosurgery, meningoencephalitis, endolumbar administration, antibiotic therapy.
p. 86 93 of the original issue
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