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Year 2022 Vol. 30 No 3

TRAUMATOLOGY AND ORTHOPEDICS

E.L. MATVEEVA, A.G. GASANOVA, S.N. LUNEVA, A.M. ERMAKOV

CARBOHYDRATE METABOLISM DISORDERS IN THE STRUCTURE OF PRIMARY AND REVISIONAL ENDOPROSHETICS OF THE HIP JOINT

Federal State Budgetary Institution "Scientific Research Center Named after Academician G. Ilizarova» Ministry of Health of the Russian Federation, Kurgan,
Russian Federation

Objective. To analyze the incidence of various disorders of carbohydrate metabolism (aseptic and septic) in patients with primary and revision hip arthroplasty.
Methods. The paper analyzes the data of anamnesis, morphometry and basic indicators of carbohydrate metabolism in the blood of patients prior the revision hip surgery. The first group (n=236) included patients with revision hip arthroplasty without infectious complications after primary arthroplasty. The second group (n=141) included the patients with serologically confirmed periprosthetic infection. The comparison group (n=188) included patients examined prior primary hip arthroplasty. Statistical methods were used to assess the incidence of type 1 and type 2 diabetes mellitus, impaired glucose tolerance and obesity - a preclinical form of impaired carbohydrate metabolism.
Results. The highest incidence of carbohydrate metabolism disorders was found in patients with periprosthetic hip joint infection. In patients with revision hip arthroplasty, the incidence of carbohydrate metabolism disorders is higher than in patients with primary arthroplasty.
Conclusion. Incidence evaluation of carbohydrate metabolism disorders in patients with revision hip arthroplasty showed the need to develop the additional laboratory criteria for preoperative preparation, examination and postoperative management in patients with periprosthetic infection. Since it is a known fact that in patients with disorders of carbohydrate metabolism, infections join faster, and infectious diseases are more severe to reduce the risk of developing instability of the hip joint endoprosthesis for this category of patients; a set of measures is required that involve the use of routine laboratory tests (glycemic monitoring) as well as the development of new approaches in protocols and clinical guidelines.

Keywords: revision hip arthroplasty, periprosthetic infection, diabetes mellitus, impaired glucose tolerance, body mass index
p. 281-287 of the original issue
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Address for correspondence:
640014, Russian Federation,
Kurgan. M.Ulyanova Street, 6,
Federal State Budgetary Institution «Scientific Research Center named after Academician G.A.Ilizarov» of the Ministry of Health
of the Russian Federation,
tel. 8 (3522) 45-05-38,
e-mail: gasanova.08@mail.ru,
Gasanova Anna G.
Information about the authors:
Matveeva Elena L., MD (Biol.), Leading Researcher of the Department of Preclinical and Laboratory Reseach of the Federal State Budgetary Institution «Scientific Research Center Named after Academician G.A. Ilizarov» of the Ministry of Health of the Russian Federation, Kurgan, Russian Federation.
http://orcid.org/0000-0002-7444-2077
Gasanova Anna G., Junior Researcher of the Department of Preclinicla and Laboratory Reseach of the Federal State Budgetary Institution «Scientific Research Center Named after Academician G.A. Ilizarov» of the Ministry of Health of the Russian Federation, Kurgan, Russian Federation.
http://orcid.org/0000-0001-7734-2808
Luneva Svetlana N., MD (Biol.), Professor, Leading Reseacher of the Department of Preclinicla and Laboratory Reseach of the Federal State Budgetary Institution «Scientific Research Center Named after Academician G.A. Ilizarov» of the Ministry of Health of the Russian Federation, Kurgan, Russian Federation.
https://orcid.org/0000-0002-0294-2398
Ermakov Artem M., PhD, Researcher of the Laboratory of the Clinic of Purulent Osteology, Physician of the Purulent Traumatology and Orthopedic Department No 1 of the Federal State Budgetary Institution «National Medical Research Center for Traumatology and Orthopedics Named after Academician G.A. Ilizarov” of the Ministry of Health of the Russian Federation, Kurgan, Russian Federation.
https://orcid.org/0000-0002-5420-4637
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