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Khirurgii

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Year 2020 Vol. 28 No 6

REVIEWS

A.V. NOVOZHILOV 1, 2, M.O. MOVSISYAN 1, S.E. GRIGOREV 1, 2, E.G. GRIGORYEV 2, 3

GIANT CHOROIDAL MELANOMA METASTASIS TO THE LIVER IN YOUNG WOMAN

Irkutsk Regional Clinical Hospital 1,
Irkutsk State Medical University 2,
Irkutsk Scientific Centre of Surgery and Traumatology 3, Irkutsk
The Russian Federation

A rare case of a young woman with a single giant metastasis of spindle-cell choroidal melanoma to the liver is described. A 32 year-old woman underwent left ocular enucleation for choroidial melanoma 8 years ago. Ultrasound examination has been diagnosed the liver pathology when she was in the 8th month of pregnancy. Later, the pathology was confirmed during a caesarean section. After delivery, the patient was referred to the oncological dispensary, where metastatic melanoma was confirmed histologically based on a transcutaneous needle biopsy. Five courses of chemotherapy have been proved to be ineffective. The woman was hospitalized to the portal hypertension department of the regional hospital. A scrupulous oncological examination revealed a solitary nature of metastasis. Its volume reached 2338 cm3, unchanged parenchyma – 951 cm3. Angioarchitecture of the liver was thoroughly studied based on MSCT-angiography findings and invasive selective celiacography. The peripheral hepatic arterial branches were deformed and fragmented with pronounced recalibration which specified a malignant process. Arterial vessels of the left lobe were unchanged. The parietal branching was traced along the whole length. The right and median veins were involved in the pathological process; the left hepatic vein was intact. In view of ineffective adjuvant therapy and disease progression, the patient underwent right lateral hemihepatectomy. The early postoperative period was uneventful. One year and ten months later during the examination the patient reported about her good life quality. She is now being followed up by oncologist.

Keywords: choroidea, melanoma, liver metastasis, chemotherapy, right-lateral hemihepatectomy
p. 739-744 of the original issue
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Address for correspondence:
664003, Russian Federation,
Irkutsk, Krasnoe Vosstanie Str., 1,
Irkutsk State Medical University,
the Hospital Surgery Department,
mobile tel. +7 9025 111 027,
e-mail: egg@iokb.ru,
Grigoryev Eugene G.
Information about the authors:
Novozhilov Alexandr V., PhD, Associate Professor of the Hospital Surgery Department, Irkutsk State Medical University, Head of the Portal Hypertension Department, Irkutsk Regional Clinical Hospital, Irkutsk, Russian Federation.
http://orcid.org/0000-0003-1957-287X
Movsisyan Mikael O., Surgeon, the Portal Hypertension Department, Irkutsk Regional Clinical Hospital, Irkutsk, Russian Federation.
http://orcid.org/0000-0003-2070-9263
Grigorev Sergey E., PhD, Associate Professor of the Hospital Surgery Department, Irkutsk State Medical University, Surgeon, the Portal Hypertension Department, Irkutsk Regional Clinical Hospital, Irkutsk, Russian Federation.
http://orcid.org/0000-0003-0254-8240
Grigoryev Eugene G., MD, Professor, Corresponding Member of RAS, Supervisor, Irkutsk Scientific Centre of Surgery and Traumatology, Head of the Hospital Surgery Department, Irkutsk State Medical University, Irkutsk, Russian Federation.
http://orcid.org/0000-0002-5082-7028
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