Year 2013 Vol. 21 No 5

EXPERIMENTAL SURGERY

B.S. SUKOVATYKH, A.V. IVANOV, N.M. VALUSKAYA, E.V. GERASIMCHUK

THE INFLUENCE OF LATE IMPLANTATION FABRIC REACTION ON THE CHOICE OF POLYPROPYLENE ENDOPROSTHESIS FOR PREVENTIVE SUBAPONEUROTIC PLASTY OF THE ABDOMINAL WALL

SBEE HPE "Kursk State Medical University",
The Russian Federation

Objectives. To study the late fabric reaction of the abdominal wall to subaponeurotic implantation of easy polypropylene endoprostheses and determine the most optimal material for the preventive endoprostheses on this basis.
Methods. Two facilitated endoprostheses served as the materials for the research: easy polypropylene and super easy polypropylene polyvinylidene fluoride mesh endoprostheses. The standard polypropylene endoprosthesis was used as control one. Thread thickness of a standard polypropylene endoprosthesis is 0,12 mm, an easy one 0,09 mm, a super easy one 0,07 mm. Experimental study was carried out in the central research laboratory of Kursk State Medical University on 33 Chinchilla rabbits, divided into 3 groups, 9 animals in each. A standard endoprosthese was implanted subaponeurotically on the muscles of the abdominal wall in the control group, in the first experimental one easy endoprosthese, in the second experimental super easy endoprostheses. Microscoping and microphotographing have been performed by means of the optical system consisting of the light microscope of Leica CME, DCM 500 digital ocular camera and the FUTURE WINJOE program included in the package of an ocular camera.
Results. The standard polypropylene endoprosthesis possesses ability of fast and reliable formation of a rough deformed connective-tissue capsule by the 30th day of the experiment. Inflammatory aseptic reaction to implantation of an easy polypropylene endoprosthesis remains within 120 days then the soft connective-tissue capsule is formed. Inflammatory aseptic reaction in response to implantation of a super easy endoprosthesis is twice shorter in comparison with an easy artificial one and is completed after 60 days with the formation of a very fine capsule.
Conclusions. The super easy polypropylene polyvinylidene endoprosthesis doesnt cause the long inflammatory reaction and is considered as an optimal material for a preventive endoprosthesis.

Keywords: mesh endoprostheses, abdominal wall plasty, late fabric reaction
p. 11 17 of the original issue
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Address for correspondence:
305041, Rossiiskaia Federatsiia, g. Kursk. ul. K. Marksa, d. 3, GBOU VPO Kurskii gosudarstvennyi meditsinskii universitet, kafedra obshchei khirurgii,
e-mail: SukovatykhBS@kursksmu.net,
Sukovatykh Boris Semenovich
Information about the authors:
Sukovatykh B.S. MD, professor, a head of the chair of general surgery SEI HPE of "Kursk State Medical University"
Ivanov A.V. MD, professor, a head of the chair of histology, cytology and embryology of SEI HPE "Kursk State Medical University".
Valuskaya N.M. PhD, a n assistant of the chair of general surgery of SEI HPE "Kursk State Medical University"
Gerasimchuk E.V. An ordinator of the chair of general surgery of SEI HPE "Kursk State Medical University"
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