Year 2013 Vol. 21 No 1

PRACTICAL CASES

I.P. SHTURICH, S.N. ERMASHKEVICH

GASTROINTESTINAL STROMAL TUMOR OF THE DUODENUM

EE Vitebsk State Medical University
The Republic of Belarus

The article presents a clinical case of the gastrointestinal stromal tumor of the duodenum.
In a 74-year-old woman during the surgery for stenosis of the Vaters papilla and obstructive jaundice, the tumor in the 3 section of the duodenum, 4 cm in diameter was revealed. Cholecystectomy, wedge resection of the duodenal tumor, transduodenal papillosphincterotomy and papillosphincteroplasty with the duodenal defect suturing and choledochostomy on Halsted were carried out in the patient. At the pathohistological study, the removed formation was presented as a gastrointestinal stromal tumors (GIST) of the duodenum (CD 117+). The patient hadnt any recurrence during 6 months after the surgery.
The data concerning epidemiology, clinical manifestation, diagnostics and treatment methods of this pathology are presented on the basis of the literature review.
Duodenal GIST is a rare disease, characterized by a predominantly local expansion, rarely involving lymph nodes and no tendency to metastases. Resection within healthy tissue and segmental resection of the duodenum are the method of choice at the treatment of duodenal GIST. Surgical treatment of extensive primary tumors or the metastasis or recurrent GIST of the duodenum should be integrated into a multimodal therapeutic concept that includes pancreatoduodenal resection and the targeted therapy with tyrosine kinase inhibitors.

Keywords: gastrointestinal stromal tumor, duodenum, surgical treatment, local resection of the duodenum
p. 111 116 of the original issue
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Address for correspondence:
210023, Respublika Belarus', g. Vitebsk, pr. Frunze, h.27, UO Vitebskii gosudarstvennyi meditsinskii universitet, kafedra gospital'noi khirurgii s kursami urologii i detskoi khirurgii,
e-mail: ivan.shturich@mail.ru,
Shturich Ivan Pavlovich
Information about the authors:
Shturich I.P. PhD, associate professor, chair of hospital surgery with the course of urology and pediatric surgery. Educational Establishment "Vitebsk State Medical University."
Ermashkevich S.N. Assistant of hospital surgery chair with course of urology and pediatric surgery Educational Establishment "Vitebsk State Medical University."
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