Year 2013 Vol. 21 No 1

REVIEWS

I.I. PIKIRENIA 1, SH.Z. SHARIPOV 1, O.S. BOGUSHEVICH 2

BILIARY STRICTURES AFTER ORTHOTOPIC LIVER TRANSPLANTATION

SEE Belarusian Medical Academy of Postgraduate Education 1,
Committee on Healthcare of Minsk Municipal Executive Committee, 2, Minsk
The Republic of Belarus

A review of the research dedicated to study the risk factors of biliary complications development after liver transplantation is presented in the article. The literature analysis has shown that despite on the appreciable achievements in the liver transplantation, there is still high incidence of the biliary complications development in the postoperative period while treating patients with the terminal stage of liver lesion caused by cirrhosis and a series of focal diseases.
The most wide spread types of biliary complications developed after orthotopic transplantations are considered the following: biliary and biliary-digestive anastomosis incompetence, their stricture as well as the non-anastomotic strictures of the biliary ducts. Among the variety of factors influencing the biliary complications development in the postoperative period are: prolonged transplant cold ischemia, blood circulation disturbance in the bile ducts, technical problems. Summarizing the literature data, risk factors of the non-anastomotic strictures can be subdivided into three main groups: ischemic, immunological and induced by salts of the bile acids.
Presence of the variety of risk factors for the biliary complications development requires further investigation and working out of methods for prevention of the biliary complications development after orthotopic liver transplantations.

Keywords: orthotopic liver transplantation, biliary complications, non-anastomotic biliary strictures
p. 105 110 of the original issue
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Address for correspondence:
210013, Respublika Belarus', g. Minsk, ul. P. Brovki, d. 3, kor. 3, GUO Belorusskaia meditsinskaia akademiia poslediplomnogo obrazovaniia, kafedra transplantologii,
e-mail: pik-med@tut.by,
Pikirenia Ivan Ivanovich
Information about the authors:
Pikirenia I.I. PhD, associate professor, head of the transplantation chair of SEE Belarusian Medical Academy of Postgraduate Education.
Sharipov Sh.Z. A post-graduate student of the cardiac surgery chair with the course of transplantation of SEE Belarusian Medical Academy of Postgraduate Education.
Bogushevich O.S. PhD, chief surgeon of Committee of Health Care of Minsk municipal executive committee.
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