Year 2011 Vol. 19 No 4




Objectives. To evaluate the effect of CVP on the blood loss during the liver transplantation.
Methods. 68 patients who underwent the liver transplantation were included in the retrospective analysis. The patients were divided into two groups. In the first group, CVP was maintained at a level no higher than 8 mm Hg, in the second group no less than 9 mm Hg.
Results. It was established that maintaining of CVP no higher than 8 mm Hg can reduce blood loss and amount of transfusions and does not increase the need for renal replacement therapy. Reducing the number of transfusions leads to decrease in the frequency of bacterial complications and, consequently, shortens the duration of stay in the intensive care unit.
Conclusions. Maintaining of CVP at a low level during the liver transplantation is pathogenetically justified and effective.

Keywords: liver transplantation, blood loss, central venous pressure
p. 77 - 82 of the original issue
  1. Institutional variability in transfusion practice for liver transplantation / Y. Ozier [et al.] // Anesth. Analg. 2003. Vol. 97, N 3. P. 671-679.
  2. The impact of intraoperative transfusion of platelets and red blood cells on survival after liver transplantation / M. T. de Boer [et al.] // Anesth. Analg. 2008. Vol.106, N 1. P. 32-44.
  3. Intraoperative blood losses and transfusion requirements during adult liver transplantation remain difficult to predict / A. Steib [et al.] // Can. J. Anaesth. 2001. Vol. 48, N 11. P. 1075-1079.
  4. New insights into the coagulopathy of liver disease and liver transplantation / M. Senzolo [et al.] // World J. Gastroenterol. 2006. Vol. 48, N 12. P. 7725-7736.
  5. Effects of phlebotomy and phenylephrine infusion on portal venous pressure and systemic hemodynamics during liver transplantation / L. Massicotte [et al.] // Transplantation. 2010. Vol.89, N 8. P. 920-927.
  6. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group / A. S. Levey [et al.] // Ann. Intern. Med. 1999. Vol. 130, N 6. P. 461-470.
  7. Intraoperative fluid management during orthotopic liver transplantation / R. A. Schroeder [et al.] // J. Cardiothorac. Vasc. Anesth. 2004. Vol. 18, N 4. P. 438-441.
  8. Low central venous pressure reduces blood loss in hepatectomy / W. D. Wang [et al.] // World J. Gastroenterol. 2006. Vol. 12, N 6. P. 935-939.
  9. Anesthetic management of hepatic transplantation / Y. Ozier [et al.] // Curr. Opin Anaesthesiol. 2008 Vol. 21, N 3. P. 391-400.
  10. Effect of hepatic venous sphincter contraction on transmission of central venous pressure to lobar and portal pressure / W. Lautt [et al.] // Can. J. Physiol. Pharmacol. 1987 Vol. 65, N 11. P. 2235-2243.
  11. Alexander, . Infections in the transplant recipient / . Alexander, K. Hanson // Liver transplant patient / eds. P. G. Killenberg, P. A. Clavien. 3-rd ed. Blackwell Publishing, 2006. P. 439-460.
  12. Fishman, J. A. Infection in organ-transplant recipients / J. A. Fishman, R. H. Rubin // Engl. J. Med. 1998. Vol. 338, N 24. P. 1741-1751.
  13. Effect of intraoperative fluid management on outcome after intraabdominal surgery / V. Nisanevich [et al.] // Anesthesiology. 2005. Vol. 103, N 1. P. 25-32.
Contacts | ©Vitebsk State Medical University, 2007-2023