Year 2009 Vol. 17 No 2




The up-to-date tendencies in diagnostics and treatment of the articular cartilage defects in the form of the review lecture are summarized in the article. The data concerning the structure and functions of the cartilage tissue, its various zones construction, many-sided role of chondrocytes and extracellular matrix are presented. The analysis of different causes resulting in damage and occurrence of cartilage covering defects of the synovial joints is given.

Keywords: cartilage, joint, defect, pathology
p. 130 - 135 of the original issue
  1. Articular cartilage biology / M. Ulrich-Vinther [et al.] // J. Am. Acad. Orthop Surg. 2003. Vol. 11. P. 421-430.
  2. Eckstein, F. The effects of exercise on human articular cartilage / F. Eckstein, M. Hudelmaier, R. Putz // Journal of Anatomy. 2006. Vol. 208, N 4. P. 491-512.
  3. Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis / J. Degroot [et al.] // Arthritis Rheum. 2004. Vol. 50. P. 1207-1215.
  4. Fithian, D. Patellar instability: the Lyon experience / D. Fithian, Ph. Neyret, E. Servien // Current Orthopaedic Practice. 2008. Vol. 19, N 3 P. 328-338.
  5. Outcomes of microfracture for traumatic chondral defects of the knee: Average 11-year follow-up / J. R. Steadman [et al.] // Arthroscopy. 2003. Vol. 19. P. 477-484.
  6. DeFranco, M. J. A Comprehensive Review of Partial Anterior Cruciate Ligament Tears / M. J. DeFranco, B. R. Bach // The Journal of Bone & Joint Surgery. 2009. Vol. 91-A, N 1. P. 198-208.
  7. Induction of chondrocyte apoptosis following impact load / J. Borrelli [et al.] // J. Orthop Trauma. 2003. Vol. 17. P. 635-641.
  8. Erggelet, C. Principles of Cartilage Repair / C. Erggelet, B. R. Mandelbaum. Springer, 2008. 121 p.
  9. Gerdeman, A. C. Whats New in Sports Medicine / A. C. Gerdeman, M. V. Hogan, M. D. Miller // The Journal of Bone & Joint Surgery. 2009. Vol. 91-A, N 1. P. 241-256.
  10. Analysis of Tibiofemoral Cartilage Deformation in the Posterior Cruciate Ligament-Deficient Knee / S. K. Van de Velde [et al.] // The Journal of Bone & Joint Surgery. 2009. Vol. 91-A, N 1. P. 167-175.
  11. Autologous chondrocyte implanation compared with microfracture in the knee: A randomized trial / G. Knutsen [et al.] // The Journal of Bone & Joint Surgery. 2004. Vol. 86-A. P. 455-464.
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