This journal is
indexed in Scopus
Year 2018 Vol. 26 No 5
T.A. STUPINA, M.A. STEPANOV, N.I. ANTONOV
STRUCTURAL REORGANIZATION OF THE KNEE ARTICULAR CARTILAGE IN DISTRACTION
FEMORAL OSTEOSYNTHESIS COMBINED WITH BONE PLATE
Russian Ilizarov Scientific Center “Restorative Traumatology and Orthopaedics”, Kurgan,
The Russian Federation
Objective. To analyze the dynamics of changes in the knee articular cartilage in the distraction femoral osteosynthesis combined with a bone plate.
Methods. The articular cartilage of the knee joint was studied experimentally using X-ray, histological and quantitative methods techniques in six mongrel dogs in the distraction femoral osteosynthesis with the rate of 1 mm for four times combined with bone plate. The studies were carried out 30 and 90 days after the plate fixation.
Results. In the distraction femoral osteosynthesis combined with a bone plate, an active osteogenesis was observed with forming a typical normoplastic regenerated bone. The period of fixation with the bone plate was 90 days. The knee function in the period of lengthening and up to 30 days of fixation was limited to 90°, the range of motion by the end of the experiment was 130-140° with presenting active static-and-dynamic function of the limb. The destructive changes in the articular cartilage manifested themselves in the zonal structure disorder, fibration visualization of the intercellular substance of the intermediate zone superficial and top parts, substantial decrease in the intercellular substance thickness, volumetric density and chondrocyte area, cell death, while proliferation was suppressed. Disturbance of basophilic line integrity was noted, as well as penetration of vessels into the cartilage, and phenomena of the osteoclastic resorption in the subchondral zone.
Conclusions. When performing distraction femoral osteosynthesis combined with a bone plate destructive changes were revealed in the articular cartilage of the knee joint. The low value of isogenic group proportion and the penetration of vessels into the cartilage evidenced of regressive hyaline cartilage changes and unfavorable functional prognosis. The degree of manifestations of the articular cartilage changes with the studied method of femoral lengthening leads to the conclusion that the development of the technologies optimal for functional rehabilitation should be continued in further experimental studies.
- Shchourov VA, Popkov DA, Laptev OV. The effect of early active movements on the rates of the knee function recovery after surgical femoral lengthening. Genii Ortopedii. 2004;(1):30-35. http://ilizarov-journal.com/index.php/go/article/view/1351/1328 (in Russ.)
- Sun XT, Easwar TR, Manesh S, Ryu JH, Song SH, Kim SJ, Song HR. Complications and outcome of tibial lengthening using the Ilizarov method with or without a supplementary intramedullary nail: a case-matched comparative study. J Bone Joint Surg Br. 2011 Jun;93(6):782-87. doi: 10.1302/0301-620X.93B6.25521
- Rose REÑ. Femoral lengthening using the Ilizarov technique. West Indian Med J. 2006 Dec;55(6):420-24. https://pdfs.semanticscholar.org/bc37/15e7b305dcd89d11885501d70ed7d950499e.pdf
- Fragomen AT, Rozbruch SR. The mechanics of external fixation. HSS J. 2007 Feb;3(1):13-29. Published online 2006 Dec 21. doi: 10.1007/s11420-006-9025-0
- Gordon JE, Manske MC, Lewis TR, O’Donnell JC, Schoenecker PL, Keeler KA. Femoral lengthening over a pediatric femoral nail: results and complications. J Pediatr Orthop. 2013 Oct-Nov;33(7):730-36. doi: 10.1097/BPO.0b013e3182a122a1
- Pavlova VN, Pavlov GG, Shostak NA, Slutskii LI. Sustav: Morfologiia, klinika, diagnostika, lechenie. Moscow, RF: Med inform agenstvo; 2011. 552 p. https://www.ozon.ru/context/detail/id/5664881/ (in Russ.)
- Stepanov MA, Antonov NI, Borzunov DYu. Experimental Approval of Combined Fixation for Femur Lengthening. Travmatologiia i Ortopediia Rossii. 2017;23(3):95-102. doi: 10.21823/2311-2905-2017-23-3-95-102 (in Russ.)
- Novikov KI, Subramanyam KN, Muradisinov SO, Novikova OS, Kolesnikova ES. Cosmetic lower limb lengthening by Ilizarov apparatus: what are the risks? Clin Orthop Relat Res. 2014 Nov;472(11):3549-56. doi: 10.1007/s11999-014-3782-8 (in Russ.)
- Nakamura E, Mizuta H, Sei A, Takagi K. Knee articular cartilage injury in leg lengthening. Histological studies in rabbits. Acta Orthop Scand. 1993 Aug;64(4):437-40. https://www.tandfonline.com/doi/pdf/10.3109/17453679308993662
- Stanitski DF, Rossman K, Torosian M. The effect of femoral lengthening on knee articular cartilage: the role of apparatus extension across the joint. J Pediatr Orthop. 1996 Mar-Apr;16(2):151-54. https://www.ncbi.nlm.nih.gov/pubmed/8742275
- Cai G, Yang L, Saleh M, Coulton L. The effect of tibial diaphyseal lengthening on the longitudinal growth of the tibia. J Pediatr Orthop B. 2007 Nov;16(6):403-7. doi: 10.1097/BPB.0b013e3282f103ae
- Li G, Yin J, Gao J, Cheng TS, Pavlos NJ, Zhang C, Zheng MH. Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes. Arthritis Res Ther. 2013;15(6):223. doi: 10.1186/ar4405
- Makushin VD. Gonarthrosis: alternative methods of surgical treatment. Kurgan, RF: Zaural’e; 2010. 625 p. (in Russ.)
- Kim HK, Bian H, Aya-ay J, Garces A, Morgan EF, Gilbert SR. Hypoxia and HIF-1alpha expression in the epiphyseal cartilage following ischemic injury to the immature femoral head. Bone. 2009 Aug;45(2):280-88. doi: 10.1016/j.bone.2009.03.665
- Kawcak CE, McIlwraith CW, Norrdin RW, Park RD, James SP. The role of subchondral bone in joint disease: a review. Equine Vet J. 2001 Mar;33(2):120-26. doi: 10.1111/j.2042-3306.2001.tb00589.x
640014, The Russian Federation,
Kurgan, M. Ulyanova Str., 6,
Russian Ilizarov Scientific Center
“Restorative Traumatology and Orthopaedics”,
Laboratory of Morphology.
Tel. office: +7 3522 41 52 27,
Tatyana A. Stupina
Stupina Tatyana A., MD, Senior Researcher of the Laboratory of Morphology, Russian Ilizarov Scientific Center “Restorative Traumatology and Orthopaedics”, Kurgan, Russian Federation.
Stepanov Mikhail A., PhD, Leading Researcher of the Experimental Laboratory, Russian Ilizarov Scientific Center “Restorative Traumatology and Orthopaedics”, Kurgan, Russian Federation.
Antonov Nicolai I., PhD, Researcher of the Experimental Laboratory, Russian Ilizarov Scientific Center “Restorative Traumatology and Orthopaedics”, Kurgan, Russian Federation.
V.D. SHYSHCHUK1, S.I. REDKO1, M.N. OGIENKO2, D.V. OVECHKIN1, L.V. TOMIN1
DISTURBANCES OF REPARATIVE OSTEOGENESIS IN THE HYPOVOLEMIA AND THEIR CORRECTION IN EXPERIMENT
Sumy State University 1,
Sumy City Clinical Hospital ¹5 2, Sumy,
Objective. To study reparative osteogenesis features in a long tubular bone of rats with moderate isoosmolar dehydration and the determination of the possibility to correlate the morphofunctional changes, caused by dehydration using the drug Actovegin.
Methods. In male Wistar rats in the control (n=21) and experimental (n=21) groups, the trauma was simulated by applying a perforated defect in the middle third of the both tibia bones diaphysis. Moderate dehydration was achieved by total water deprivation for 6-7 days until 6-10% animal weight loss was reached. In the experimental group, Actovegin was administered 2 mg intramuscularly every other day. The introduction of the drug began immediately after the injury and continued until the end of the experiment. On the 3rd, 15th and 24th day, histological examination, morphometry and scanning electron microscopy was carried out to study morphological changes in rat tibial reclaims.
Results. Moderate isoîsmolar dehydration caused a disruption of cellular and tissue balance which slowed down the bone regeneration process without changing the staging of their course. As a result, a normal bone callus did not have time to form in expected terms. Actovegin stimulated the reparative bone regeneration, the ratio of tissue components of the regenerate changed, the area increased and the qualitative properties of coarse-fiber and lamellar bone tissues were improved in comparison with the indices of animals in the control group. An increase in the total area and diameter of the vessels in the regenerate was registered.
Conclusions. The use of the drug Àctovegin permitted to optimize the blood circulation in the damaged segment and to accelerate the processes of bone restructuring and maturation resulting in the formation of a full-blown bone callus.
- Hernlund E, Svedbom A, Ivergard M, Compston J, Cooper C, Stenmark J, McCloskey EV, Jönsson B, Kanis JA. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos. 2013;8:136. doi: 10.1007/s11657-013-0136-1
- Malinovskii EL, Nadyrov EA, Nikolaev VI. Optimizatsiia reparativnogo osteogeneza pri politravme. Novosti Khirurgii. 2011;19 (5):17-22. http://www.surgery.by/pdf/full_text/2011_5_3_ft.pdf (in Russ.)
- Gulevsky AK, Abakumova YS, Moiseyeva NN, Ivanov YG. Influence of cord blood fraction (below 5 kDa) in reparative processes during subchronic ulcerative gastropathy. Ulcer. 2011(2011):1-9. doi: 10.1155/2011/214124
- Stelmakh A, Abrahamovych O, Cherkas A. Highly purified calf hemodialysate (Actovegin®) may improve endothelial function by activation of proteasomes: a hypothesis explaining the possible mechanisms of action. Med Hypotheses. 2016 Oct;95:77-81. doi: 10.1016/j.mehy.2016.09.008
- Søndergard SD, Dela F, Helge JW, Larsen S. Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci. 2016 Oct;16(7):801-7. doi: 10.1080/17461391.2015.1130750
- Lee P, Nokes L, Smith PM. No effect of intravenous Actovegin® on peak aerobic capacity. Int J Sports Med. 2012 Apr;33(4):305-9. doi: 10.1055/s-0031-1291322
- Wu SX, Cui TT, Zhao C, Pan JJ, Xu BY, Tian Y, Cui NJ. A prospective, randomized, multi-center trial to investigate Actovegin in prevention and treatment of acute oral mucositis caused by chemoradiotherapy for nasopharyngeal carcinoma. Radiother Oncol. 2010 Oct;97(1):113-18. doi: 10.1016/j.radonc.2010.08.003
- Guekht A, Skoog I, Edmundson S, Zakharov V, Korczyn AD. ARTEMIDA Trial (A Randomized Trial of Efficacy, 12 Months International Double-Blind Actovegin): A Randomized Controlled Trial to assess the efficacy of actovegin in poststroke cognitive impairment. Stroke. 2017 May;48(5):1262-1270. doi: 10.1161/STROKEAHA.116.014321
- Soboleva AD. Reaktsiia kletok i tkanei na obezvozhivanie. Novosibirsk, SSSR: Nauka; 1975. 64 p. (in Russ.)
- Korzh NA, Dedukh NV. Reparativnaia regeneratsiia kosti: sovremennyi vzgliad na problemu. Stadii regeneratsii (soobshch 1). Ortopediia, Travmatologiia i Protezirovanie. 2006;(1)77-84. (in Russ.)
- Logosha AI, Slisarenko AV, Ogienko MN, Bumeister VI, Prikhod’ko OA. Reparativnyi osteogenez trubchatykh kostei v usloviiakh narusheniia vodno-solevogo obmena. Georgian Medical News. 2013;(10):80-86. http://www.geomednews.org (in Russ.)
- Oryan A, Monazzah S, Bigham-Sadegh A. Bone injury and fracture healing biology. Biomed Environ Sci. 2015 Jan;28(1):57-71. doi: 10.3967/bes2015.006
Sumy, Sanatornaya Str., 31,
Medical Institute of Sumy State University,
Department of Orthopedics
Tel. mob.: 380 066 08 27 869,
Sergiy I. Redko
Shyshchuk Volodymir D., MD, Professor, Head of the Department of Orthopedics and Traumatology of Medical Institute, Sumy State University, Sumy, Ukraine.
Redko Sergiy I., Assistant of the Department of Orthopedics and Traumatology of Medical Institute, Sumy State University, Sumy, Ukraine.
Ogienko Maksym N., PhD, Physician, Sumy City Clinical Hospital ¹5, Sumy, Ukraine.
Ovechkin Denys V., PhD, Associate Professor of the Department of Orthopedics and Traumatology of Medical Institute, Sumy State University, Sumy, Ukraine.
Tomin Lubov V., Post-Graduate Student of the Department of Orthopedics and Traumatology of Medical Institute, Sumy State University, Sumy, Ukraine.
GENERAL & SPECIAL SURGERY
O.F. SOVTUS, R.V. SABADOSH
USE OF ENDOVASCULAR AND COMBINED INTERVENTIONS IN OBLITERATING OCCLUSIVE-STENOTIC ARTERIAL DISEASES OF THE LOWER LIMBS
Ivano-Frankivsk National Medical University, Ivano-Frankivsk,
Objective. To improve the results of treatment in patients with lower limb artery occlusive-stenotic diseases, where open operations are impossible or involve a high risk, by using endovascular interventions.
Methods. 53 patients have been treated, they underwent endovascular revascularization of lower limb artery different segments (I group – aortoiliac with or without femoropopliteal; IIÀ – femoropopliteal; IIB – femoropopliteal and infrapopliteal; III – infrapopliteal) with/without of the additional open operations on other segments. During the year a technical success of the procedures, the primary and secondary patency of intervention zones, the frequency of conservation and the degree of limb ischemia were assessed.
Results. The technical success was achieved in 94.3% of patients, 1-year secondary patency was achieved in 92.5%, the preservation of the lower limbs was achieved in 96.2%. In group I, where 60% of patients underwent hybrid operations (endovascular stage - on aortoiliac segment), a positive technical result was obtained in all the patients; stent thrombosis, necrotic processes, ischemia above grade IIA (Fontaine) were not observed during one year. Identical results were obtained in the IIA group. In the III group, which was based on patients with total occlusion of the lower leg and foot main arteries or total circular calcification of their post-occlusal segments, the technical success was 84.6%, the one-year primary patency was 76.9%, and limb salvage was 100%. In Group IIB these indicators were 91.7, 75.0 and 83.3%, respectively.
Conclusions. The careful application of endovascular interventions in stenosis and occlusions of the lower limbs arteries allows achieving technical success, primary and secondary patency of the revascularization zone and one-year limb salvage in 88.7-96.2% of patients. Endovascular treatment can be recommended as the method of choice in complete occlusion of the lower leg and foot main arteries, total circular calcification of their post-occlusal segments and for revascularization of aortoiliac segment in case of its combined lesions with the femoropopliteal segment at hybrid operations.
- Mehaffey JH, Hawkins R, Fashandi A, Tracci MC, Cherry K, Kron I, Upchurch G, Robinson WP. Lower extremity bypass is associated with lower short-term major adverse limb events and equivalent major adverse cardiac events compared with endovascular intervention in a national cohort with critical limb ischemia. J Vascr Surg. 2017 Jan;65(Is 1):e4-e5. doi: 10.1016/j.jvs.2016.10.018
- Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG; TASC II Working Group, Bell K, Caporusso J, Durand-Zaleski I, Komori K, Lammer J, Liapis C, Novo S, Razavi M, Robbs J, Schaper N, Shigematsu H, Sapoval M, White C, White J, Clement D, Creager M, Jaff M, Mohler E 3rd, Rutherford RB, Sheehan P, Sillesen H, Rosenfield K. Inter-society consensus for the management of peripheral arterial disease (TASC II). Eur J Vasc Endovasc Surg. 2007;33 (Suppl 1):S1-75. doi: 10.1016/j.ejvs.2006.09.024
- Tendera M, Aboyans V, Bartelink ML, Baumgartner I, Clément D, Collet JP, Cremonesi A, De Carlo M, Erbel R, Fowkes FG, Heras M, Kownator S, Minar E, Ostergren J, Poldermans D, Riambau V, Roffi M, Röther J, Sievert H, van Sambeek M, Zeller T. ESC Guidelines on the diagnosis and treatment of peripheral artery diseases: Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries: the task force on the diagnosis and treatment of peripheral artery diseases of the european society of cardiology (ESC). Eur Heart J. 2011 Nov;32(22):2851-906. doi: 10.1093/eurheartj/ehr211
- Aboyans V, Ricco JB, Bartelink MLEL, Björck M, Brodmann M, Cohnert T, Collet JP, Czerny M, De Carlo M, Debus S, Espinola-Klein C, Kahan T, Kownator S, Mazzolai L, Naylor AR, Roffi M, Röther J, Sprynger M, Tendera M, Tepe G, Venermo M, Vlachopoulos C, Desormais I. Editor’s Choice – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2018;55(3):305-68. doi: 10.1016/j.ejvs.2017.07.018
- Stoner MC, Calligaro KD, Chaer RA, Dietzek AM, Farber A, Guzman RJ, Hamdan AD, Landry GJ, Yamagu DJ. Reporting standards of the Society for Vascular Surgery for endovascular treatment of chronic lower extremity peripheral artery disease. J Vasc Surg. 2016 Jul;64(1):e1-e21. doi: 10.1016/j.jvs.2016.03.420
- Mills JL Sr, Conte MS, Armstrong DG, Pomposelli FB, Schanzer A, Sidawy AN, Andros G. The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: risk stratification based on wound, ischemia, and foot infection (WIfI). J Vasc Surg. 2014 Jan;59(1):220-34.e1-2. doi: 10.1016/j.jvs.2013.08.003
- TASC Steering Committee, Jaff MR, White CJ, Hiatt WR, Fowkes GR, Dormandy J, Razavi M, Reekers J, Norgren L. An update on methods for revascularization and expansion of the TASC lesion classification to include below-the-knee arteries: a supplement to the inter-society consensus for the management of peripheral arterial disease (TASC II). Ann Vasc Dis. 2015;8(4):343–57. doi: 10.1177/1358863X15597877
- Olin JW, White CJ, Armstrong EJ, Kadian-Dodov D, Hiatt WR. Peripheral artery disease: evolving role of exercise, medical therapy, and endovascular options. J Am Coll Cardiol. 2016 Mar 22;67(11):1338-57. doi: 10.1016/j.jacc.2015.12.049
- Clair DG, Beach JM. Strategies for managing aortoiliac occlusions: access, treatment and outcomes. Expert Rev Cardiovasc Ther. 2015 May;13(5):551-63. doi: 10.1586/14779072.2015.1036741
- Antoniou GA, Georgiadis GS, Antoniou SA, Makar RR, Smout JD, Torella F. Bypass surgery for chronic lower limb ischaemia. Cochrane Database Syst Rev. 2017 Apr 3;4:CD002000. doi: 10.1002/14651858.CD002000.pub3
- Goloshchapov-Aksenov RS, Shugushev ZKh, Matveev DV, Maximkin DA, Lakunin KYu. Evaluation of the effectiveness of endovascular treatment of patients with obliterating atherosclerosis of lower limb arteries with long occlusions of the superficial femoral artery. Vestn RUDN. Ser Meditsina.2017;21(2):234-45. doi: 10.22363/2313-0245-2017-21-2-234-245 (in Russ.)
- Gray BH, Diaz-Sandoval LJ, Dieter RS, Jaff MR, White CJ. SCAI expert consensus statement for infrapopliteal arterial intervention appropriate use. Catheter Cardiovasc Interv. 2014 Oct 1;84(4):539-45. doi: 10.1002/ccd.25395
- TASC Steering Committee, Jaff MR, White CJ, Hiatt WR, Fowkes GR, Dormandy J, Razavi M, Reekers J, Norgren L. An update on methods for revascularization and expansion of the TASC lesion classification to include below-the-knee arteries: a supplement to the inter-society consensus for the management of peripheral arterial disease (TASC II). Vasc Med. 2015 Oct;20(5):465-78. doi: 10.1177/1358863X15597877
Ivano-Frankivsk, Galitskaya Str., 2,
Ivano-Frankivsk National Medical University,
Surgery Department of the Stomatological Faculty,
Rostyslav V. Sabadosh
Sovtus Oleg F., Post-Graduate Student of the Surgery Department of the Stomatological Faculty, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.
Sabadosh Rostislav V., MD, Professor of the Surgery Department of the Stomatological Faculty, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine.
R.E. KALININ, I.A. SUCHKOV, N.D. MZHAVANADZE, E.A. KLIMENTOVA, O.N. ZHURINA, S.A. ISAKOV
INTRINSIC COAGULATION CASCADE FACTORS AND HEMOSTATIC MARKERS OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PERIPHERAL ARTERY DISEASE
Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan,
The Russian Federation
Objective. To assess the activity of intrinsic coagulation cascade factors of coagulation and hemostatic markers of endothelial dysfunction in patients with atherosclerotic peripheral artery disease (PAD) before and after endovascular treatment.
Methods. The study included 80 patients with PAD in the stage IIB-III of the disease according to Pokrovsky-Fontaine classification. 40 patients with PAD underwent endovascular interventions on the femoropopliteal segment (group A) and 40 patients underwent the conservative treatment (group B). Patients underwent physical examination, ankle-brachial index measurement (ABI), duplex ultrasound (DUS) and digital substraction angiography. 3 and 6 months after treatment patients underwent the same procedures. At inclusion of patients in the study and 3 months after the surgery, peripheral venous blood samples were collected to assess the activity of VIII, IX, XI, von Willebrand factor (VWF), protein Ñ (PrC) and metabolites of nitric oxide II (NO).
Results. In patients of the group À mean values of activity VIII, IX, XI factors and VWF were increased in comparison with the norm before the surgery. After 3 months the results shown a greater increase in activity VIII, IX, XI factors, the elevated levels of VWF remained in the reduction of NO metabolites. In patients of the group B the mean activity values of IX, XI factors and VWF were increased with normal levels of NO metabolites and PrC.
Conclusions. The analysis of the initial state of the hemostasis system in patients with atherosclerotic peripheral artery disease allows us to conclude that the hypercoagulable state develops against the background of a normal anticoagulation potential. Operative procedures provide a further shift towards a hypercoagulable state and impaired functional activity of endothelium
- Fowkes FG, Rudan D, Rudan I, Rudan I, Aboyans V, Denenberg JO, McDermott MM, Norman PE, Sampson UKA, Williams LJ, Mensah GA, Criqui MH, Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis. Lancet. 2013;382(9901):1329-40.doi: 10.1016/S0140-6736(13)61249-0
- Ye W, Liu CW, Ricco JB, Mani K, Zeng R, Jiang J. Early and late outcomes of percutaneous treatment of Trans Atlantic Inter-Society Consensus class C and D aorto-iliac lesions. J Vasc Surg. 2011 Jun;53(6):1728-37. doi: 10.1016/j.jvs.2011.02.005
- Pokrovskii AV, Ivandaev AS, red. Sostoianie sosudistoi khirurgii v Rossii v 2016 godu. Moscow, RF; 2017. 77 p. http://docplayer.ru/52369292-Sostoyanie-sosudistoy-hirurgii-v-rossii-v-2016-godu.html (in Russ.)
- Katsanos K, Al-Lamki SA, Parthipun A, Spiliopoulos S, Patel SD, Paraskevopoulos I, Zayed H, Diamantopoulos A. Peripheral stent thrombosis leading to acute limb ischemia and major amputation: incidence and risk factors in the aortoiliac and femoropopliteal arteries. Cardiovasc Intervent Radiol. 2017;40(3):351-59. Published online 2016 Dec 5. doi: 10.1007/s00270-016-1513-0
- Lei X, Reheman A, Hou Y, Zhou H, Wang Y, Marshall AH, Liang C, Dai X, Li BX, Vanhoorelbeke K, Ni H. Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis. Thromb Haemost. 2014 Feb;111(2):279-89. doi: 10.1160/TH13-06-0490
- Delvaeye M, Conway EM. Coagulation and innate immune responses: can we view them separately? Blood. 2009 Sep 17;114(12):2367-74. doi: 10.1182/blood-2009-05-199208
- Hoffman M, Pawlinski R. Hemostasis: old system, new players, new directions. Thromb Res. 2014 May;133(Suppl 1):S1-2. doi: 10.1016/j.thromres.2014.03.001
- Yakushin SS, Filippov EV. Value assessment of endothelial function at the population level (according to the research MERIDIAN-RO). Nauka molodykh - EruditioJuvenium. 2013;(3):48-55. http://naukamolod.rzgmu.ru/uploads/art/art72_9a005b.pdf (in Russ.)
- Zanolini D, Merlin S, Feola M, Ranaldo G, Amoruso A, Gaidano G, Zaffaroni M, Ferrero A, Brunelleschi S, Valente G, Gupta S, Prat M, Follenzi. Extrahepatic sources of factor VIII potentially contribute to the coagulation cascade correcting the bleeding phenotype of mice with hemophilia A. Haematologica. 2015 Jul;100(7):881-92. doi: 10.3324/haematol.2014.123117
- Babichev AV. The role of endothelium in hemostasis mechanisms. Pediatr. 2013;4(1):122-27. https://cyberleninka.ru/article/n/rol-endoteliya-v-mehanizmah-gemostaza (in Russ.)
- Kalinin RE, Zviagina VI, Pshennikov AS, Suchkov IA, Matveeva IV. Fotokolorimetricheskii metod opredeleniia urovnia metabolitov oksida azota v syvorotke krovi. Astrakhan Med Zhurn. 2010;5(1):188-89. http://www.astmedj.ru/archive (in Russ.)
- Cassar K, Bachoo P, Ford I, Greaves M, Brittenden J. Markers of coagulation activation, endothelial stimulation and inflammation in patients with peripheral arterial disease. Eur J Vasc Endovasc Surg. 2005 Feb;29(2):171-76. doi: 10.1016/j.ejvs.2004.11.001
- Kazantsev AV, Korymasov EA. Diagnostika progressiruiushchego techeniia obliteriruiushchego ateroskleroza bedrenno-podkolenno-bertsovoi lokalizatsii. Fundam Issledovaniia. 2011;(1):62-67. https://www.fundamental-research.ru/ru/article/view?id=15809 (in Russ.)
- Gogia S, Neelamegham S. Role of fluid shear stress in regulating VWF structure, function and related blood disorders. Biorheology. 2015;52(5-6):319-35. doi: 10.3233/BIR-15061
- Vischer UM. Von Willebrand factor, endothelial dysfunction, and cardiovascular disease. J Thromb Haemost. 2006 Jun;4(6):1186-93. doi: 10.1111/j.1538-7836.2006.01949.x
390026, The Russian Federation,
Ryazan, Vysokovoltnaya Str., 9,
Ryazan State Medical University
Named after Academician I.P. Pavlov,
Department of Cardiovascular,
And Topographic Anatomy,
Tel. mobile: +7 4912 46 08 03,
Igor A. Suchkov
Kalinin Roman E., MD, Professor, Rector, Head of the Department of Cardiovascular, X-Ray Endovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
Suchkov Igor A., MD, Associate Professor, Vice-Rector for Research and Innovative Development, Professor of the Department of Cardiovascular, X-Ray Endovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
Mzhavanadze Nina J., PhD, Assistant of the Department of Cardiovascular, X-Ray Endovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
Klimentova Emma A., Post-Graduate Student of the Department of Cardiovascular, X-Ray Endovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
Zhurina Olga N., PhD, Head of Clinical and Diagnostic Laboratory of the Clinical Research Center for Hematology, Oncology and Immunology, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
Isakov Sergey A., MD, Professor of the Dermatovenereology Department, Ryazan State Medical University named after Academician I.P. Pavlov, Ryazan, Russian Federation.
L.A. LICHMAN, S.E. KATORKIN, P.S. ANDREEV, O.E. DAVYDOVA, A.P. MIHAYLICHENKO
PILONIDAL SINUS: NEW APPROACH TO OPERATIVE TREATMENT
Samara State Medical University, Samara,
The Russian Federation
Objective. To improve the results of treatment in patients with the pilonidal sinus by developing and implementing a new method of surgical treatment.
Methods. By random sampling, patients (n=111) were divided into two groups. In the control group (n = 68), a conventional technique was used – the excision of the pilonidal sinus with sutures according to Moshkovich. In the main group (n=43) the developed operative technique – the excision of the pilonidal sinus with wound closure by the method of marsupialization with a continuous suture – was used.
Results. The average duration of immediate surgical treatment: the excision of the pilonidal sinus with closure of the wound by the method of marsupialization with a continuous suture made up 21.9±4.3 min., the excision of the pilonidal sinus with Moshkovich sutures – 30.9±5.4 min., statistically significant differences were not found. With ultrasound of soft tissues in the area of the postoperative wound, the infiltration zone in the main group was 5.3±1.0 mm, in patients of the control group 10.7±0.92 mm, statistically significant differences were found, p <0.05.
In the postoperative period, the patients of the main group showed less intensity of the pain syndrome. Severity of pain in the area of a postoperative wound by VAS for the first day in the main group was 3.6±0.4 and in the control group 5.6±0.6; on the third day, 2.07±0.35 and 4.7±0.6, respectively; on the fifth day 0.96±0.33 and 3.9±0.63; on the tenth day – 0±0.005 and 0.45 ± 0.33. Statistical processing of the obtained results revealed statistically significant differences for the first (p<0.05), the third (p <0.05), the fifth (p < 0.05) day. A statistically significant (χ2=14.8, p<0.05) decrease in the number of early postoperative complications (suppuration of the postoperative wound, inconsistency of cutaneous sutures) in the main group to 4.6% was obtained.
Conclusions. The use of a continuous suture combined with marsupialization to close the wound defect after excision of the pilonidal sinus is an effective method of surgical treatment and allows improving the results of treatment in patients with this pathology.
- Vorob’ev GI, red. Osnovy koloproktologii. Rostov na Donu, RF: Feniks; 2001. 416 p. https://www.avito.ru/novosibirsk/knigi_i_zhurnaly/osnovy_koloproktologii._uchebnoe_posobie_15624 68083 (in Russ.)
- Lurin IA, Tsema IeV. Aetiology and pathogenesis of pilonidal disease (review article). Koloproktologiia.2013;(3):35-50. http://www.gnck.ru/pdf/journal_3_45_2013.pdf (in Russ.)
- Magomedova ZK, Chernyshova EV, Groshilin VS. Advantages and application of a new method of surgical treatment of patients with recurrent pilonidal sinus. Ul’ian Med-Biol Zhurn. 2016;(2):98-105. http://medbio.ulsu.ru/images/numbers/2016/2_2016.pdf. (in Russ.)
- Dul’tsev IuV, Rivkin VL. Epitelial’nyi kopchikovyi khod. Moscow, SSSR: Meditsina; 1988. 128 p. http://med-books.by/hirurgiya/2913-epitelialnyy-kopchikovyy-hod-dulcev-yuv-rivkin-vl-1988-god-128-s.html (in Russ.)
- Lichman LA, Katorkin SE, Andreev PS. Results of surgical treatment of patients with epithelial coccygeal cyst. Vrach-Aspirant. 2017;81(2):19-24. https://elibrary.ru/item.asp?id=28407303 (in Russ.)
- Anderson AW. Hair extracted from an ulcer. Boston Med Surg J. 1847;36:74-76.
- Denisenko VL. Optimizatsiia lecheniia epitelial’nogo kopchikovogo khoda, oslozhnennogo abstsessom. Novosti Khirurgii. 2008;16(1):55-61. http://www.surgery.by/pdf/full_text/2008_1_7_ft.pdf (in Russ.)
- Gulov MK, Zubaidov TN. Choice of surgical treatment of patients with pilonidal fistula. Vestn Avitsenny. 2012;(3):34-39. http://vestnikavicenna.tj/web/upload/global/pdf/2012/3_2012.pdf (in Russ.)
- Buie L. Practical proctology. Philadelphia: WB Saunders; 1937. 451 ð.
- Gecim IE, Goktug UU, Celasin H. Endoscopic Pilonidal Sinus Treatment Combined With Crystalized Phenol Application May Prevent Recurrence. Dis Colon Rectum. 2017 Apr;60(4):405-407. doi: 10.1097/DCR.0000000000000778
- Harris C, Sibbald RG, Mufti A, Somayaji R. Pilonidal Sinus Disease: 10 Steps to Optimize Care. Adv Skin Wound Care. 2016 Oct;29(10):469-78. doi: 10.1097/01.ASW.0000491324.29246.96
- Dessily M, Charara F, Ralea S, Allé JL. Pilonidal sinus destruction with a radial laser probe: technique and first Belgian experience. Acta Chir Belg. 2017 Jun;117(3):164-68. doi: 10.1080/00015458.2016.1272285
- Isik A, Idiz O, Firat D. Novel Approaches in Pilonidal Sinus Treatment. Prague Med Rep. 2016;117(4):145-52. doi: 10.14712/23362936.2016.15
- Cherkasov MF, Galashokyan KM, Startsev YuM, Cherkasov DM. Vacuum therapy in treatment of the pilonidal sinus disease. Koloproktologiia. 2016;(1):35-39. http://www.gnck.ru/pdf/journal_1_55_2016.pdf (in Russ.)
443079, The Russian Federation,
Samara, Karl Marks Ave., 164 B,
Clinic of Samara
State Medical University,
Department and Clinic of Hospital Surgery,
Tel. office: +7 927 900 88 58,
Leonid A. Lichman
Lichman Leonid A., Surgeon, Surgical Unit, Clinic of Hospital Surgery, Samara State Medical University, Samara, Russian Federation.
Katorkin Sergey E., PhD, Associate Professor, Head of the Department and Clinic of Hospital Surgery, Samara State Medical University, Samara, Russian Federation.
Andreev Pavel S., PhD, Assistant of the Department of Hospital Surgery, Coloproctologist, Coloproctology Unit, the Clinic of Hospital Surgery, Samara State Medical University, Samara, Russian Federation.
Davydova Olga E., Coloproctologist, Coloproctology Unit, the Clinic of Hospital Surgery, Samara State Medical University, Samara, Russian Federation.
Mikhailichenko Alena P., Ultrasound Diagnostic Doctor, Samara State Medical University, Samara, Russian Federation.
S.V. SHAKHRAY, Y.M. GAIN, M.Y. GAIN, D.V. KUDRYTSKI
EFFICIENCY ASSESSMENT OF COMPLEX TREATMENT OF ANAL CONDYLOMATOSIS
Belarusian Medical Academy of Post-Graduate Education, Minsk,
The Republic of Belarus
Objective. To evaluate the clinical efficacy of the combined method of anal condylomatosis treatment, based on laser tumor destruction and immunomodulatory therapy.
Methods. The study included 2 stages. At the first retrospective stage the analysis of 60 patients with anal condylomatosis treatment using laser and electrosurgical destruction methods was performed, immune therapy was not used. The duration of the wound epithelialization, recurrence rate were studied. In the second, prospect study 60 patients were observed; the physical methods of condyloma destruction were supplemented with the therapy of human recombinant interferon α2b and imiquimod.
Results. According to the data obtained during the study, laser and electrosurgical destruction are effective methods of anal condylomatosis treatment. Laser destruction has certain advantages: higher epithelialization rate in the area of exposure (ANOVA, p=0.00001) and fewer recurrences of the disease in terms of 2 years’ follow-up (Pearson’s chi-squared test, χ2 = 4.89; p=0.0270). The separate use of physical methods in the treatment of this pathology leads to a much greater number of relapses compared with the complex approach, where laser and electrocoagulation destruction is supplemented with immune and antiviral treatment by human recombinant interferon α2b and imiquimod (Cochran’s Q test, Q=9.591549, p = 0.022378). Also the time interval without the disease progressing was longer in this groups (Kaplan-Meier test, p=0.01528).
Conclusions. The results of the study allow us to state that the use of laser radiation for the destruction of anal condylomas has several advantages over electrocoagulation: a lower risk of recurrence, a shorter period of epithelialization of the wound. The use of immunomodulatory therapy with human recombinant interferon α2b and topical application of imiquimod significantly reduces the frequency of the disease recurrence.
- Prilepskaia VN, Rogovskaia SI, Kondrikov NI, Sukhikh GT. Papillomavirusnaia infektsiia: diagnostika, lechenie i profilaktika. Moscow, RF: MEDpress-inform; 2007. 32 p. (in Russ.)
- Aubin F, Prétet JL, Jacquard AC, Saunier M, Carcopino X, Jaroud F, Pradat P, Soubeyrand B, Leocmach Y, Mougin C, Riethmuller D. Human papillomavirus genotype distribution in external acuminata condylomata: a Large French National Study (EDiTH IV). Clin Infect Dis. 2008 Sep 1;47(5):610-15. doi: 10.1086/590560
- Narvskaia OV. Virus papillomy cheloveka. Epidemiologiia, laboratornaia diagnostika i profilaktika papillomavirusnoi infektsii. Infektsiia i Immunitet. 2011;1(1):15-22. https://www.iimmun.ru/iimm/article/viewFile/23/22 (in Russ.)
- Fleischer AB Jr, Parrish CA, Glenn R, Feldman SR. Condylomata acuminata (genital warts): patient demographics and treating physicians. Sex Transm Dis. 2001 Nov;28(11):643-47. https://journals.lww.com/stdjournal/Fulltext/2001/11000/Condylomata
- Desai S, Wetten S, Woodhall SC, Peters L, Hughes G, Soldan K. Genital warts and cost of care in England. Sex Transm Infect. 2011 Oct;87(6):464-68. doi: 10.1136/sti.2010.048421
- Östensson E, Fröberg M, Leval A, Hellström AC, Bäcklund M, Zethraeus N, Andersson S. Cost of preventing, managing, and treating human papillomavirus (HPV)-related diseases in Sweden before the introduction of quadrivalent HPV vaccination. PLoS One. 2015;10(9): e0139062. Published online 2015 Sep 23. doi: 10.1371/journal.pone.0139062
- Redklif K. Evropeiskie standarty diagnostiki i lecheniia zabolevanii, peredavaemykh polovym putem: per. s angl. Moscow, RF: Med lit; 2006. 272 p. https://www.ozon.ru/context/detail/id/1492842 (in Russ.)
- Shakhrai SV, Kudritskii DV, Gain IuM, Gain MIu. Comparative estimation of efficiency of the modern methods of invasive treatment of perianal area condylomatosis. Innovats Tekhnologii v Meditsine. 2018;(1):29-35. (in Russ.) https://elibrary.ru/item.asp?id=32490418
- Bencini PL, Guida S, Cazzaniga S, Pellacani G, Galimberti MG, Bencini M, Naldi L. Risk factors for recurrence after successful treatment of warts: the role of smoking habits. J Eur Acad Dermatol Venereol. 2017 Apr;31(4):712-16. doi: 10.1111/jdv.14086
- Volkov VG, Zakharova TV. Practice of using CO2-laser surgery in complex therapy of cervical pathology, associated with human papilloma virus. Vestn Novykh Med Tekhnologii. 2000;7(1):95-97. https://elibrary.ru/item.asp?id=25136262 (in Russ.)
- Al-Zahrani D, Raddadi A, Massaad M, Keles S, Jabara HH, Chatila TA, Geha R. Successful interferon-alpha 2b therapy for unremitting warts in a patient with DOCK8 deficiency. Clin Immunol. 2014 Jul;153(1):104-108. doi: 10.1016/j.clim.2014.04.005
- Yanofsky VR, Patel RV, Goldenberg G. Genital warts: a comprehensive review. J Clin Aesthet Dermatol. 2012 Jun;5(6):25-36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390234/
- Petersen CS, Bjerring P, Larsen J, Blaakaer J, Hagdrup H, From E, Obergaard L. Systemic interferon alpha-2b increases the cure rate in laser treated patients with multiple persistent genital warts: a placebo-controlled study. Genitourin Med. 1991 Apr;67(2):99-102. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1194640
220013, The Republic of Belarus,
Minsk, P. Brovki Str., 3-3,
Belarusian Medical Academy of Post-Graduate Education,
Department of Urgent Surgery,
Tel.: +375 17 225 88 10,
Yuri M. Gain
Shakhrai Siarhei V., MD, Professor of the Department of Urgent Surgery, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
Gain Yuri M., MD, Professor, Vice-Rector for Scientific Work, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
Gain Mikhail Yu., PhD, Associate Professor of the Department of Urgent Surgery, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
Kudrytski Dzmitry V., Post-Graduate Student of the Department of Urgent Surgery, Belarusian Medical Academy of Post-Graduate Education, Minsk, Republic of Belarus.
A.I. RUNDO, V.A. KOSINETS., I.V. SAMSONOVA
PHOTOTHERAPY IMPACT ON THE INTENSITY OF MAC387-POSITIVE MACROPHAGES EXPRESSION IN DIABETIC FOOT SYNDROME
Vitebsk State Medical University, Vitebsk,
The Republic of Belarus
Objective. To study the expression of the inflammatory response marker anti-macrophage antibody MAC387 in the wound zone in patients with diabetic foot syndrome in case of local and combined phototherapy.
Methods. The expression intensity of macrophages marker MAC387 in the serial microscopic biopsy specimens of the wound defect was analyzed in 158 with purulent-necrotic lesions of the feet against the background of diabetes mellitus type 2 at the surgical department of Vitebsk City Emergency Clinical Hospital. Using the randomization method, 3 groups were formed: 1 – control (57 people); 2 – with additional use in the treatment of phototherapy locally over the wound surface (51 people); 3 – with additional use in the treatment of combined phototherapy locally and intravenously (52 people). The effect of phototherapy was assessed by immunohistochemical staining of the biopsy material using monoclonal antibodies to macrophages anti-macrophage antibody MAC387 on 1, 3-5, 7, 14 days from the beginning of treatment.
Results. The wound process in diabetic foot syndrome is accompanied by an increase in the expression intensity of anti-macrophage antibody MAC387, which can serve as a marker of the duration of its course. The use of a local phototherapy is accompanied with an increased level of the macrophages marker ÌÀÑ387 expression intensity, which demonstrates the positive effect of blue and red light on the inflammatory process course. Combined phototherapy promotes a pronounced increase in the macrophage marker expression by the 7th day and a decrease by the 14th day of therapeutic measures, which indicates a faster onset of the wound process proliferative phase.
Conclusions. In diabetic foot syndrome, the expression intensity of macrophage MAC387 marker changes in the area of the wound defect, which can serve as a criterion for assessing the duration of the wound healing process. The use of local and combined phototherapy allows normalizing the course of the wound process and accelerating the healing of the lower limbs trophic ulcers in patients with diabetic foot syndrome.
- Saloko OB, Bogdan EL, Shepel’kevich AP, Shchaveleva MV, Yarosh EA. Rasprostranennost’ khronicheskikh oslozhnenii sakharnogo diabeta v Respublike Belarus’ (po dannym Respublikanskogo registra «Sakharnyi diabet»). Lechebnoe Delo. 2016;(5):31-34. http://lech-delo.by/wpcontent/uploads/content_ld_5_51_2016.jpg (in Russ.)
- IDF Diabets atlas [Internet]. 8th ed. [cited 2017 Sep 7]. Available from: http://diabetesatlas.org/resources/2017-atlas.html
- Bublik EV, Galstian GR. Epidemiologiia i patogeneticheskie faktory sindroma diabeticheskoi stopy u bol’nykh s terminal’noi stadiei khronicheskoi pochechnoi nedostatochnosti, nakhodiashchikhsia na dialize. Sakhar Diabet. 2007;(3):10-17. https://cyberleninka.ru/article/v/epidemiologiya-i-patogeneticheskie-faktory-sindroma-diabeticheskoy-stopy-u-bolnyh-s-terminalnoy-stadiey-hronicheskoy-pochechnoy (in Russ.)
- Tellechea A, Leal EC, Kafanas A, Auster ME, Kuchibhotla S, Ostrovsky Y, Tecilazich F, Baltzis D, Zheng Y, Carvalho E, Zabolotny JM, Weng Z, Petra A, Patel A, Panagiotidou S, Pradhan-Nabzdyk L, Theoharides TC, Veves A. Mast cells regulate wound healing in diabetes. Diabetes. 2016 Jul;65(7):2006-19. doi: 10.2337/db15-0340
- Umerov EE. Osobennosti morfologicheskoi struktury kozhi pri ishemicheskikh troficheskikh iazvakh s uchetom makrofagal’noi aktivnosti vospalitel’nogo infil’trata. Svit Meditsini ta Biologii. 2013;(4):89-91. https://womab.com.ua/smb-2013-04-1/3938 (in Russ.)
- Varyushina EA, Moskalenko VV, Lebedeva TP, Bubnov AN, Simbirtsev AS. Interleukin-1p application for local treatment of purulent and necrotic lesions of lower extremities. Med Immunologiia. 2008;10(4-5):439-48. http://www.spbraaci.ru/files/2008-4-5-439-448.pdf (in Russ.)
- Vinnik IuS, Salmina AB, Drobushevskaia AI, Tepliakova OV, Pozhilenkova EA, Kotikov AR. Osobennosti patogeneza dlitel’no nezazhivaiushchikh ran. Novosti Khirurgii. 2011;19(3):101-10. http://www.surgery.by/pdf/full_text/2011_3_16_ft.pdf (in Russ.)
- Maruyama K, Asai J, Ii M, Thorne T, Losordo DW, D’Amore PA. Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. Am J Pathol. 2007 Apr;170(4):1178-91. doi: 10.2353/ajpath.2007.060018
- Gibson DJ, Schulftz G. Chronic wound diagnostic for matrix metalloproteinase. Wound Healing Southern Africa. 2009;2:68-70. http://www.woundhealingsa.co.za/index.php/WHSA/article/view/51
- Sharifian Z, Bayat M, Alidoust M, Farahani RM, Bayat M, Rezaie F, Bayat H. Histological and gene expression analysis of the effects of pulsed low-level laser therapy on wound healing of streptozotocin-induced diabetic rats. Lasers Med Sci. 2014 May;29(3):1227-35. doi: 10.1007/s10103-013-1500-5
- de Loura Santana C, Silva D de F, Deana AM, Prates RA, Souza AP, Gomes MT, de Azevedo Sampaio BP, Shibuya JF, Bussadori SK, Mesquita-Ferrari RA, Fernandes KP, França CM. Tissue responses to postoperative laser therapy in diabetic rats submitted to excisional wounds. PLoS One. 2015 Apr 24;10(4):e0122042. doi: 10.1371/journal.pone.0122042
- Li Y, Zhang J, Xu Y, Han Y, Jiang B, Huang L, Zhu H, Xu Y, Yang W, Qin C. Effects of 630 nm red and 460 nm blue light emitting diode irradiation on healing of the skin wound in Japanese big-ear white rabbit. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2017 Jun 20;39(3):301-306. doi: 10.3881/j.issn.1000-503X.2017.03.001
- Houreld N, Abrahamse H. He-Ne laser irradiation stimulates proliferation and migration of diabetic wounded fibroblast cells. In: Waynant R, Tata DB. (eds). Proceedings of Light-Activated Tissue Regeneration and Therapy Conference. Springer, Boston, MA; 2008;12. ð. 221-32. https://link.springer.com/chapter/10.1007%2F978-0-387-71809-5_21
- Zhang H, Liu S, Yang X, Chen N, Pang F, Chen Z, Wang T, Zhou J, Ren F, Xu X, Li T. LED Phototherapy with gelatin sponge promotes wound healing in mice. Photochem Photobiol. 2018 Jan;94(1):179-85. doi: 10.1111/php.12816
210023, The Republic of Belarus,
Vitebsk, Frunze Ave., 27,
Vitebsk State Medical University,
Department of Operative Surgery
And Topographic Anatomy,
Tel. office.: +375 212 24-08-09,
Tel. mob.: +375 33 645-12-01,
Aliaksei I. Rundo
Rundo Aliaksei I., Assistant of the Department of Operative Surgery and Topographic Anatomy, Vitebsk State Medical University, Vitebsk, Republic of Belarus.
Kosinets Vladimir A., MD, Professor of the Department of Hospital Surgery with courses of Urology and Pediatric Surgery, Vitebsk State Medical University, Vitebsk, Republic of Belarus.
Samsonova Inna V., PhD, Associate Professor, Head of the Department of Pathological Anatomy with a course of Forensic Medicine, Vitebsk State Medical University, Vitebsk, Republic of Belarus.
D.V. OSIPENKO, A.A. SILANAU, A.A. PIACHONKIN
ANATOMIC SUBSTANTIATION OF SELECTION OF THE PLACE OF PUNCTURE AND INTRODUCTION OF THE CENTRAL VENOUS CATHETER IN CARDIOSURGERY PATIENTS
Gomel Regional Clinical Cardiology Center, Gomel,
The Republic of Belarus
Objective. To carry out an ultrasound evaluation of the features of clinical anatomy and the mutual location of the internal jugular vein and common carotid artery at different levels of the neck scanning to determine the optimal point for puncture and introduction of a central venous catheter in patients undergoing surgical interventions on the heart. There is the ultrasonic assessment of features of clinical anatomy and the relative positioning of the internal jugular vein and common carotid artery in cardiac surgery patients at various levels of a neck scanning for selection of the optimum point for puncture of central veins.
Methods. The study included 61 patients who were subjected to ultrasound scanning of the neck vessels from two sides at the following levels: first scanning point – the apex of the triangle formed by the legs of the sternocleidomastoid muscle; the second scanning point is 3-5 cm above the 1st scanning point (approximately at the point of intersection of the external jugular vein with the sternocleidomastoid muscle). The following vessel parameters were recorded: the distance from the skin to the vein wall, the size of the internal jugular vein and its position relative to the common carotid artery.
Results. The distance from the skin to the wall of the internal jugular vein, both on the left and on the right, was significantly greater at the 2nd point of scanning, compared to the 1st scan point. The right internal jugular vein was dominant and had a maximum size at the 1st scan point in the largest number of patients.
The following regularity is described: in the Trendelenburg position with a slope of 15° and a rotation of the head by 45° at the first point of scanning, only in 33 (54%) and 34 (56%) patients left and right classical (lateral) location of the internal jugular vein was observed; at the second point of scanning – respectively, only in 26 (43%) and 28 (46%) patients.
Conclusions. The point of puncture and of the introduction of a central venous catheter located in the region of the apex of the triangle formed by the legs of the right sternocleidomastoid muscle is the most optimal and can be recommended for the internal jugular vein catheterization. Taking into account the considerable variability in the location of the internal jugular vein, the introduction of a central venous catheter is recommended to be performed under ultrasound guidance.
- Nobl’ VE, Nel’son B, Sutingko AN. UZI pri neotlozhnykh i kriticheskikh sostoianiiakh: per. s angl. Moscow, RF: Med. lit; 2009. 240 p. http://www.booksmed.com/luchevaya-diagnostika/860-uzi-pri-neotlozhnyx-i-kriticheskix-sostoyaniyax.html (in Russ.)
- Marochkov AV, Stabletskii AD, Stefanenkova VP. Thrombus formation in venous catheters depending on the site of their disposition in the central veins. Anesteziol Reanimatol. 1985 Mar-Apr;(2):52-55.
- Hoffman T, Du Plessis M, Prekupec MP, Gielecki J, Zurada A, Tubbs RS, Loukas M. Ultrasound-guided central venous catheterization: A review of the relevant anatomy, technique, complications, and anatomical variations. Clin Anat. 2017 Mar;30(2):237-250. doi: 10.1002/ca.22768
- Rouzen M, Latto IaP, Ng U Sheng. Chrezkozhnaia kateterizatsiia tsentral’nykh ven: per. s angl. Moscow, RF: Meditsina; 1986. 160 p. http://www.nehudlit.ru/books/chreskozhnaya-kateterizatsiya-tsentralnykh-ven.html (in Russ.)
- Lamperti M, Bodenham AR, Pittiruti M, Blaivas M, Augoustides JG, Elbarbary M, Pirotte T, Karakitsos D, Ledonne J, Doniger S, Scoppettuolo G, Feller-Kopman D, Schummer W, Biffi R, Desruennes E, Melniker LA, Verghese ST. International evidence-based recommendations on ultrasound-guided vascular access. IntensiveCareMed. 2012 Jul;38(7):1105-17. doi: 10.1007/s00134-012-2597-x
- Tsikunov AE. Sbornik formul po matematike. S-Petersburg, RF: Piter; 2002. 160 p. http://library.bntu.by/sites/default/files/novye-postupleniya/cikunov-e-sbornik-formul-po-matematike.pdf (in Russ.)
- Bos MJ, van Loon RF, Heywood L, Morse MP, van Zundert AA. Comparison of the diameter, cross-sectional area, and position of the left and right internal jugular vein and carotid artery in adults using ultrasound. J Clin Anesth. 2016 Aug;32:65-69. doi: 10.1016/j.jclinane.2015.12.034
- Lichtenstein D, Saifi R, Augarde R, Prin S, Schmitt JM, Page B, Pipien I, Jardin F. The Internal jugular veins are asymmetric. Usefulness of ultrasound before catheterization. Intensive Care Med. 2001 Jan;27(1):301-5.doi: 10.1007/s001340000792
- Lorchirachoonkul T, Ti LK, Manohara S, Lye ST, Tan SA, Shen L, Kang DS. Anatomical variations of the internal jugular vein: implications for successful cannulation and risk of carotid artery puncture. Singapore Med J. 2012 May;53(5):325-28. https://www.ncbi.nlm.nih.gov/pubmed/22584972
- Wang R, Snoey ER, Clements RC, Hern HG, Price D. Effect of head rotation on vascular anatomy of the neck: an ultrasound study. J Emerg Med. 2006 Oct;31(3):283-86. doi:10.1016/j.jemermed.2005.12.026
246046, The Republic of Belarus,
Gomel, Meditsinskaya Str., 4,
Gomel Regional Clinical Cardiology Center,
Department of Anesthesiology and Resuscitation
With Intensive Care Wards,
Tel./fax: +375 232 557-925;
Dzmitry V. Osipenko
Osipenko Dzmitry V., PhD, Anesthesiologist-Resuscitator, Department of Anesthesiology and Resuscitation with Intensive Care Wards, Gomel Regional Clinical Cardiology Center, Gomel, Republic of Belarus.
Silanau Aliaksandr A., anesthesiologist-resuscitator, Department of Anesthesiology and Resuscitation with Intensive Care Wards, Gomel Regional Clinical Cardiology Center, Gomel, Republic of Belarus.
Piachonkin Aliaksei A., PhD, angiosurgeon, Head of the Vascular Surgery Unit, Gomel Regional Clinical Cardiology Center, Gomel, Republic of Belarus.
I.O. POHODENKO-CHUDAKOVA1, K.V. VILKITSKAYA1, N.I. POLIAKOVA2, I.M. BAIRIKOV3
DIAGNOSTICS METHODS OPTIMIZATION OF ODONTOGENIC ORIGIN CHRONIC INFLAMMATORY PROCESSES AND MAXILLARY SINUS NEOPLASIA
Belarusian State Medical University 1, Minsk
Maryina Gorka Central Regional Hospital 2, Maryina Gorka,
The Republic of Belarus,
Samara State Medical University 3, Samara,
The Russian Federation
Objective. To improve the diagnostics of chronic inflammatory processes of odontogenic etiology and neoplasia in the maxillary sinus.
Methods. 65 cone-beam computed tomograms of patients with X-ray signs of chronic odontogenic inflammatory processes in the maxillary sinus (main group) and 65 without sinus diseases (control group) were studied. In the main group, the age of patients was 18-74 years (mean – 42.9 years), in the control group were enrolled patients aged 18-76 years (mean – 42.5 years). Based on the data of the three-dimensional ray method, the volume of formation was calculated, the anatomical and topographical features of the structure of sinus maxillaris were studied, which resulted in the development of the severity indices of chronic odontogenic sinusitis and neoplasms extending into the lumen of the maxillary sinus. In all patients, using cone-beam computed tomography, the disease risk and severity of pathological process were determined.
Results. Maxillary sinus volume of the main group patients significantly exceeded the same in the comparison groups (p <0.05), and also depended on the sex of the examined patients. The main risk factors for the development of odontogenic etiology diseases are hyperpneumatization and the first type ratio of the lateral teeth group roots with the bottom of sinus maxillaris. The most common degree of disease is the average severity, according to the indicators of chronic odontogenic sinusitis and the severity of the neoplasm. In 62.3% of cases, the risk of developing the disease of the odontogenic etiology maxillary sinus was revealed in the control group of patients.
Conclusions. The developed severity indices of chronic odontogenic sinusitis and neoplasms extending into the lumen of the maxillary sinus make it possible to supplement the diagnostic capabilities of the three-dimensional radiation methods of the study and optimize their subsequent clinical interpretation, thereby improving the quality of the patients’ examination with the possibility of subsequent individual prophylaxis planning of the development of the disease and its treatment.
- Vishnyakov VV, Yalymova DL. Surgical treatment for chronic odontogenic maxillary sinusitis and posttreatment assessment of quality of life in patients. Vrach. 2015;(7):78-80. https://vrachjournal.ru/?q=ru/vrach-2015-07-20 (in Russ.)
- Khronicheskii sinusit - SymptoMD.ru [Elektronnyi resurs]. [Data dostupa: 2017 Sent 10]. Available from: https://symptomd.ru/icd10/j32_hronicheskiy_sinusit (in Russ.)
- Slavin RG, Spector SL, Bernstein IL, Kaliner MA, Kennedy DW, Virant FS, Wald ER, Khan DA, Blessing-Moore J, Lang DM, Nicklas RA, Oppenheimer JJ, Portnoy JM, Schuller DE, Tilles SA, Borish L, Nathan RA, Smart BA, Vandewalker ML. The diagnosis and management of sinusitis: a practice parameter update. J Allergy Clin Immunol. 2005 Dec;116(6 Suppl):S13-47. doi: 10.1016/j.jaci.2005.09.048
- Broome M, Jaques B, Monnier Y. Diagnosis and management of sinusitis of odontogenic origin. Rev Med Suisse. 2008 Oct 1;4(173):2080-82, 2084. [Article in French]
- Timofeev AA, Vesova EP, Ushko NA. Givaleks pri profilaktike posleoperatsionnykh oslozhnenii u bol’nykh s odontogennym khronicheskim gaimoritom. Sovrem Stomatologiia. 2014;(2):68-73. http://nbuv.gov.ua/UJRN/ss_2014_2_16 (in Russ.)
- Hauman CH, Chandler NP, Tong DC. Endodontic implications of the maxillary sinus: a review. Int Endod J. 2002 Feb;35(2):127-41. doi: 10.1046/j.0143-2885.2001.00524.x
- Kulakova AA, Robustova TG, Nerobeeva AI. Khirurgicheskaia stomatologiia i cheliustno-litsevaia khirurgiia: nats ruk. Moscow, RF: GEOTAR-Media; 2010. 928 p. http://www.studmed.ru/kulakov-la-robustova-tg-nerobeev-li-hirurgicheskaya-stomatologiya-i-chelyustno-licevaya-hirurgiya-nacionalnoe-rukovodstvo_5941da993bd.html (in Russ.)
- Nair UP, Nair MK. Maxillary sinusitis of odontogenic origin: cone-beam volumetric computerized tomography-aided diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Dec;110(6):e53-7. doi: 10.1016/j.tripleo.2010.06.020
- Torgashova OE. Konusno-luchevaia komp’iuternaia tomografiia kak standart obsledovaniia patsientov s radikuliarnymi kistami verkhnei cheliusti. X-Ray Art. 2015;(5):26-28. http://www.picasso-diagnostic.ru/upload/iblock/2ff/2ff543f2e792be159898ee71ecb7cf05.pdf (in Russ.)
- Zubareva AA, Chibisova MA, Dudarev AL, Shavgulidze MA. Vozmozhnosti tsifrovoi ob”emnoi tomografii v otorinolaringologii, cheliustno-litsevoi khirurgii i khirurgicheskoi stomatologii. Med Alfavit. Stomatologiia. 2012;(2):18-24. (in Russ.)
- Serova NS, Evseeva EV, Kleshchevnikova KYu, Kovalin VV, Slepushkina AV. Konusno-luchevaia komp’iuternaia tomografiia v diagnostike odontogennykh verkhnecheliustnykh sinusitov. Endodontiia Today. 2015;(2):68-71. https://elibrary.ru/item.asp?id=24346576 (in Russ.)
- Sergeev SV, Grigorkina ES. Age features of facial bones pneumatization by radiography. Fundam Issledovaniia. 2013;(2-1):162-66. https://www.fundamental-research.ru/ru/article/view?id=31076 (in Russ.)
- Uchida Y, Goto M, Katsuki T, Soejima Y. Measurement of maxillary sinus volume using computerized tomographic images. Int J Oral Maxillofac Implants. 1998 Nov-Dec;13(6):811-18. https://pdfs.semanticscholar.org/aec8/b88edf283ad1b3596b3e6a957786aec5a4c4.pdf
- Hikosaka M, Nagasao T, Ogata H, Kaneko T, Kishi K. Evaluation of maxillary sinus volume in cleft alveolus patients using 3-dimensional computed tomography. J Craniofac Surg. 2013;Jan:24(1):e23-6. doi: 10.1097/SCS.0b013e318267bdf3
- Saati S, Kaveh F, Yarmohammadi S. Comparison of cone beam computed tomography and multi slice computed tomography image quality of human dried mandible using 10 anatomical landmarks. J Clin Diagn Res. 2017: Feb;11(2):ZC13-ZC16. doi: 10.7860/JCDR/2017/20637.9253
220116, The Republic of Belarus,
Minsk, Dzerzhinsky Ave., 83,
Belarusian State Medical University,
Department of Surgical Dentistry,
Tel. office: +375 17 254-32-44,
Kristina V. Vilkitskaya
Pohodenko-Chudakova Irina O., MD, Professor, Head of the Department of Surgical Dentistry, Belarusian State Medical University, Minsk, Republic of Belarus.
Vilkitskaya Kristina V., PhD, Associate Professor of the Department of Surgical Dentistry, Belarusian State Medical University, Minsk, Republic of Belarus.
Poliakova Natalia I., Surgeon-Dentist, Maryina Gorka Central Regional Hospital, Maryina Gorka, Republic of Belarus.
Bairikov Ivan M., MD, Professor, Head of the Department and Clinic of Maxillofacial Surgery and Dentistry, Samara State Medical University, Samara, Russian Federation.
A.V. ZAPALIANSKI, O.V. KANDRATSYEVA, A.A. SVIRSKY
SURGICAL METHODS OF TREATMENT OF GIANT OMPHALOCELE IN CHILDREN
Republican Scientific and Practical Center for Pediatric Surgery, Minsk,
The Republic of Belarus
The review describes various options of classical and modern techniques of surgical treatment of congenital malformation of the anterior abdominal wall – the giant omphalocele. The main existing techniques are presented, such as primary, staged and delayed closure of the defect. Particular attention is paid to such perspective areas of the staged surgical treatment as vacuum-assisted closure, using of tissue expanders and systems with active external traction. The advantages and disadvantages of each technique are indicated and a comparative analysis of their effectiveness is carried out. Examples of new surgical options for correction of the malformation are presented, based on the achievements of modern bioengineering researches and innovative technologies. The prospects of the using the biodegradable biomaterials, such as «Alloderm» and submucosal layer of the small intestine for reconstruction of the abdominal wall and primary closure of the defect are analyzed. The review details various approaches of reconstructive surgical treatment of large abdominal wall defects in older children after the formation of ventral hernia in newborns. The application experience of the component separation technique (CST) for abdominoplasty in the period of newborns and older age is analyzed, and also the ways to improve the cosmetic and physiological results of the treatment are outlined.
- Akinkuotu AC, Sheikh F, Olutoye OO, Lee TC, Fernandes CJ, Welty SE, Ayres NA, Cass DL. Giant omphaloceles: surgical management and perinatal outcomes. J Surg Res. 2015 Oct;198(2):388-92. doi: 10.1016/j.jss.2015.03.060
- Buinewicz J, Laub D Jr. Giant omphalocele treated with intramuscular tissue expansion. Eplasty. 2014 Jan 16;14:ic3. eCollection 2014. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897219/
- Ein SH, Langer JC. Delayed management of giant omphalocele using silver sulfadiazine cream: an 18-year experience. J Pediatr Surg. 2012 Mar;47(3):494-500. doi: 10.1016/j.jpedsurg.2011.08.014
- Kumar HR, Jester AL, Ladd AP. Impact of omphalocele size on associated conditions. J Pediatr Surg. 2008 Dec;43(12):2216-19. doi: 10.1016/j.jpedsurg.2008.08.050
- Campos BA, Tatsuo ES, Miranda ME. Omphalocele: how big does it have to be a giant one? J Pediatr Surg. 2009 Jul;44(7):1474-75; author reply 1475. doi: 10.1016/j.jpedsurg.2009.02.060
- Harjai MM, Bhargava P, Sharma A, Saxena A, Singh Y. Repair of a giant omphalocele by a modified technique. Pediatr Surg Int. 2000;16(7):519-21. doi: 10.1007/s003839900331
- van Eijck FC, de Blaauw I, Bleichrodt RP, Rieu PN, van der Staak FH, Wijnen MH, Wijnen RM. Closure of giant omphaloceles by the abdominal wall component separation technique in infants. J Pediatr Surg. 2008 Jan;43(1):246-50. doi: 10.1016/j.jpedsurg.2007.09.051
- van Eijck FC, Aronson DA, Hoogeveen YL, Wijnen RM. Past and current surgical treatment of giant omphalocele: outcome of a questionnaire sent to authors. J Pediatr Surg. 2011 Mar;46(3):482-88. doi: 10.1016/j.jpedsurg.2010.08.050
- Zama M, Gallo S, Santecchia L, Bertozzi E, Zaccara A, Trucchi A, Nahom A, Bagolan P, De Stefano C. Early reconstruction of the abdominal wall in giant omphalocele. Br J Plast Surg. 2004 Dec;57(8):749-53. doi: 10.1016/j.bjps.2004.05.021
- Saxena AK, van Tuil C. Delayed three-stage closure of giant omphalocele using pericard patch. Hernia. 2008 Apr;12(2):201-3. doi: 10.1007/s10029-007-0264-x
- Zaccara A, Zama M, Trucchi A, Nahom A, De Stefano F, Bagolan P. Bipedicled skin flaps for reconstruction of the abdominal wall in newborn omphalocele. J Pediatr Surg. 2003 Apr;38(4):613-15. doi: 10.1053/jpsu.2003.50133
- De Ugarte DA, Asch MJ, Hedrick MH, Atkinson JB. The use of tissue expanders in the closure of a giant omphalocele. J Pediatr Surg. 2004 Apr;39(4):613-15. doi: 10.1016/j.jpedsurg.2003.12.022
- Kapfer SA, Keshen TH. The use of human acellular dermis in the operative management of giant omphalocele. J Pediatr Surg. 2006 Jan;41(1):216-20. doi: 10.1016/j.jpedsurg.2005.10.093
- Parida L, Pal K, Al Buainain H, Elshafei H. Staged closure of giant omphalocele using synthetic mesh. APSP J Case Rep. 2014 Sep-Dec;5(3):27. eCollection 2014 Sep. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207232/
- Alaish SM, Strauch ED. The use of Alloderm in the closure of a giant omphalocele. J Pediatr Surg. 2006 Mar;41(3):e37-39. doi: 10.1016/j.jpedsurg.2005.12.067
- Jiang W, Zhang J, Lv X, Lu C, Chen H, Xu X, Tang W. Use of small intestinal submucosal and acellular dermal matrix grafts in giant omphaloceles in neonates and a rabbit abdominal wall defect model. J Pediatr Surg. 2016 Mar;51(3):368-73. doi: 10.1016/j.jpedsurg.2015.08.005
- Martin AE, Khan A, Kim DS, Muratore CS, Luks FI. The use of intraabdominal tissue expanders as a primary strategy for closure of giant omphaloceles. J Pediatr Surg. 2009 Jan;44(1):178-82. doi: 10.1016/j.jpedsurg.2008.10.031
- Sönmez K, Onal E, Karabulut R, Turan O, T ürkyilmaz Z, Hirfanoğlu I, Kapisiz A, Başaklar AC. A strategy for treatment of giant omphalocele. World J Pediatr. 2010 Aug;6(3):274-77. doi: 10.1007/s12519-010-0016-3
- Schuster SR. A new method for the staged repair of large omphaloceles. Surg Gynecol Obstet. 1967 Oct;125(4):837-50. https://www.ncbi.nlm.nih.gov/pubmed/4227443
- Pacilli M, Spitz L, Kiely EM, Curry J, Pierro A. Staged repair of giant omphalocele in the neonatal period. J Pediatr Surg. 2005 May;40(5):785-88. doi: 10.1016/j.jpedsurg.2005.01.042
- Lee SL, Beyer TD, Kim SS, Waldhausen JH, Healey PJ, Sawin RS, Ledbetter DJ. Initial nonoperative management and delayed closure for treatment of giant omphaloceles. J Pediatr Surg. 2006 Nov;41(11):1846-49. doi: 10.1016/j.jpedsurg.2006.06.011
- Hong AR, Sigalet DL, Guttman FM, Laberge JM, Croitoru DP. Sequential sac ligation for giant omphalocele. J Pediatr Surg. 1994 Mar;29(3):413-15. doi: 10.1016/0022-3468(94)90581-9
- Shinohara T, Tsuda M. Successful sequential sac ligation for an unruptured giant omphalocele: report of a case. Surg Today. 2006 Aug;36(Is 8):707-709. doi: 10.1007/s00595-006-3223-8
- Almond SL, Goyal A, Jesudason EC, Graham KE, Richard B, Selby A, Losty PD. Novel use of skin substitute as rescue therapy in complicated giant exomphalos. J Pediatr Surg. 2006 Mar;41(3):e1-2. doi: 10.1016/j.jpedsurg.2005.11.085
- Archer LP, Billmire DA, Falcone JrRA, Warner BW. Reconstruction of an acquired abdominal wall defect in a neonate using acellular human dermis. Plast Reconstr Surg. 2006 Dec;118(Is 7):163e-166e. doi: 10.1097/01.prs.0000232215.59089.e8
- Gabriel A, Gollin G. Management of complicated gastroschisis with porcine small intestinal submucosa and negative pressure wound therapy. J Pediatr Surg. 2006 Nov;41(11):1836-40. doi: 10.1016/j.jpedsurg.2006.06.050
- Reimer MW, Yelle JD, Reitsma B, Doumit G, Allen MA, Bell MS. Management of open abdominal wounds with a dynamic fascial closure system. Can J Surg. 2008 Jun;51(3):209-14. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496576/
- Baird R, Gholoum S, Laberge JM, Puligandla P. Management of a giant omphalocele with an external skin closure system. J Pediatr Surg. 2010 Jul;45(7):E17-20. doi: 10.1016/j.jpedsurg.2010.05.004
- DeLuca FG, Gilchrist BF, Paquette E, Wesselhoeft CW, Luks FI. External compression as initial management of giant omphaloceles. J Pediatr Surg. 1996 Jul;31(7):965-67. doi: 10.1016/S0022-3468(96)90423-6
- Patkowski D, Czernik J, Baglaj SM. Active enlargement of the abdominal cavity–a new method for earlier closure of giant omphalocele and gastroschisis. Eur J Pediatr Surg. 2005 Feb;15(1):22-25. doi: 10.1055/s-2004-830542
- Morabito A, Owen A, Bianchi A. Traction-compression-closure for exomphalos major. J Pediatr Surg. 2006 Nov;41(11):1850-53. doi: 10.1016/j.jpedsurg.2006.06.044
- Kilbride KE, Cooney DR, Custer MD. Vacuum-assisted closure: a new method for treating patients with giant omphalocele. J Pediatr Surg. 2006 Jan;41(1):212-15. doi: 10.1016/j.jpedsurg.2005.10.003
- Binet A, Gelas T, Jochault-Ritz S, Noizet O, Bory JP, Lefebvre F, Belouadah M, James-Robert I, Aubert D, Bouche-Pillon Persyn MA, Poli-Merol ML, François-Fiquet C. VAC® therapy a therapeutic alternative in giant omphalocele treatment: a multicenter study. J Plast Reconstr Aesthet Surg. 2013 Dec;66(12):e373-75. doi: 10.1016/j.bjps.2013.05.010
- Verlende P, Zoltie N. A new surgical approach to exomphalos. Br J Plast Surg. 1990 Mar;43(2):241-43. doi: 10.1016/0007-1226(90)90169-Z
- Adetayo OA, Aka AA, Ray AO. The use of intra-abdominal tissue expansion for the management of giant omphaloceles: review of literature and a case report. Ann Plast Surg. 2012 Jul;69(1):104-8. doi: 10.1097/SAP.0b013e31822128f5
- Foglia R, Kane A, Becker D, Asz-Sigall J, Mychaliska G. Management of giant omphalocele with rapid creation of abdominal domain. J Pediatr Surg. 2006 Apr;41(4):704-9; discussion 704-9. doi: 10.1016/j.jpedsurg.2005.12.013
- Mehrabi V, Mehrabi A, Kadivar M, Soleimani M, Fallahi A, Khalilzadeh N. Staged repair of giant recurrent omphalocele and gastroschesis “camel-litter method”-a new technique. Acta Med Iran. 2012;50(6):388-94.
- Gross RE. A new method for surgical treatment of large omphaloceles. Surgery. 1948 Aug;24(2):277-92.
- Grob M. Conservative Treatment of Exomphalos. Arch Dis Child. 1963 Apr;38(198):148-50.
- Oquendo M, Agrawal V, Reyna R, Patel HI, Emran MA, Almond PS. Silver-impregnated hydrofiber dressing followed by delayed surgical closure for management of infants born with giant omphaloceles. J Pediatr Surg. 2015 Oct;50(10):1668-72. doi: 10.1016/j.jpedsurg.2015.06.011
- Kouame BD, Odehouri Koudou TH, Yaokreh JB, Sounkere M, Tembely S, Yapo KG, Boka R, Koffi M, Dieth AG, Ouattara O, da Silva A, Dick R. Outcomes of conservative treatment of giant omphaloceles with dissodic 2% aqueous eosin: 15 years’ experience. Afr J Paediatr Surg. 2014 Apr-Jun;11(2):170-73. doi: 10.4103/0189-6725.132825
- Pandey V, Gangopadhyay AN, Gupta DK, Sharma SP, Kumar V. Non-operative management of giant omphalocele with topical povidone-iodine and powdered antibiotic combination: early experience from a tertiary centre. Pediatr Surg Int. 2014 Apr;30(4):407-11. doi: 10.1007/s00383-014-3479-9
- Sakellaris G, Petrakis I, Vlazakis S, Kakavelakis K, Vasiliou M, Antipas S, Ntolatzas T. Management of neglected giant omphalocele with Gore-tex in a child aged 8 years. Minerva Pediatr. 2002 Oct;54(5):455-58. https://www.minervamedica.it/en/journals/minerva-pediatrica/issue.php?cod=R15Y2002N05
- Mali VP, Prabhakaran K, Patankar JZ. Management of ventral hernia after giant exomphalos with external pressure compression using helmet device. J Pediatr Surg. 2004 Aug;39(8):e1-4. doi: 10.1016/j.jpedsurg.2004.04.041
- Ramirez OM, Ruas E, Dellon AL. “Components separation” method for closure of abdominal-wall defects: an anatomic and clinical study. Plast Reconstr Surg. 1990 Sep;86(3):519-26. https://journals.lww.com/plasreconsurg/toc/1990/09000
- Wijnen RM, van Eijck F, van der Staak FH, Bleichrodt RP. Secondary closure of a giant omphalocele by translation of the muscular layers: a new method. Pediatr Surg Int. 2005 May;21(5):373-76. doi: 10.1007/s00383-005-1387-8
- van Eijck FC, van Vlimmeren LA, Wijnen RM, Klein W, Kruijen I, Pillen S, Nijhuis-van der Sanden MW. Functional, motor developmental and long-term outcome after the component separation technique in children with giant omphalocele: a case control study. J Pediatr Surg. 2013 Mar;48(3):525-32. doi: 10.1016/j.jpedsurg.2012.08.010
- Levy S, Tsao K, Cox CS Jr, Phatak UR, Lally KP, Andrassy RJ. Component separation for complex congenital abdominal wall defects: not just for adults anymore. J Pediatr Surg. 2013 Dec;48(12):2525-29. doi: 10.1016/j.jpedsurg.2013.05.067
- Pereira RM, Tatsuo ES, Simoes e Silva AC, Guimarães JT, Paixão RM, Lanna JC, Miranda ME. New method of surgical delayed closure of giant omphaloceles: Lazaro da Silva’s technique. J Pediatr Surg. 2004 Jul;39(7):1111-15. doi: 10.1016/j.jpedsurg.2004.03.064
- Kruit AS, Al-Ani SA, Jester I, Jester A. Multilayered flap technique: a method for delayed closure of giant omphalocele. Ann Plast Surg. 2016 Jun;76(6):680-83. doi: 10.1097/SAP.0000000000000589
220013, The Republic of Belarus,
Minsk, Nezavisimosti Ave., 64,
Republican Scientific and Practical
Center for Pediatric Surgery,
Pediatric Surgery Unit,
Tel. mobile: +375 29 141 91 29,
Andrei V. Zapalianski
Zapalianski Andrei V., PhD, Pediatric Surgeon, Republican Scientific and Practical Center for Pediatric Surgery, Minsk, Republic of Belarus.
Kandratsyeva Volha V., PhD, Pediatric Surgeon, Republican Scientific and Practical Center for Pediatric Surgery, Minsk, Republic of Belarus.
Svirsky Aliaksandr A., PhD, Associate Professor, Head of the Pediatric Surgery Unit, Republican Scientific and Practical Center for Pediatric Surgery, Minsk, Republic of Belarus.
L.A. BOCKERIA, O.L. BOCKERIA, F.S. GAFUROV
CURRENT STATE OF THE PROBLEM IN PREVENTION OF ATRIAL FIBRILLATION IN THE EARLY POSTOPERATIVE PERIOD AFTER CORONARY ARTERY BYPASS SURGERY
A.N. Bakulev National Medical Research Center of Cardiovascular Surgery,
The Russian Federation
Atrial fibrillation is the most frequent complication of the open heart surgery, including the coronary artery bypass grafting, often leading to a significant increase in the duration of hospital stay, worsening the course of the early and mid-term postoperative period and augmenting the economic costs of treatment.
The aim of the present review is to analyze the data on pharmacological and non-pharmacological approaches to the treatment and prevention of atrial fibrillation in the early postoperative period after the coronary artery bypass grafting. Despite the progressive development of modern antiarrhythmic drugs, the success of sinus rhythm restoration in the postoperative atrial fibrillation does not exceed 50-55%. The literature analysis has shown that biatrial overdrive pacing for the first 72 hours after the surgery is the most effective method to prevent and manage this type of arrhythmia. According to the various studies, biatrial pacing allows achieving 75-85% freedom from atrial fibrillation in the early postoperative period following coronary artery bypass grafting, that is statistically higher than with any other (either pharmacological or non-pharmacological) method of postoperative atrial fibrillation prevention and treatment. In addition, most authors note the safety of biatrial pacing in cardiac surgical patients.
- Maaroos M, Tuomainen R, Price J, Rubens FD, Jideus RL, Halonen J, Hartikainen J, Hakala T. Preventive strategies for atrial fibrillation after cardiac surgery in Nordic countries. Scand J Surg. 2013;102(3):178-81. doi: 10.1177/1457496913492671
- Melikulov AKh, Maglakelidze DA. Vozmozhnye mekhanizmy i strategii profilaktiki fibrilliatsii predserdii posle operatsii na otkrytom serdtse. Annaly Aritmologii. 2012;9(1):13-19. http://arrhythmology.pro/files/pdf/aa_1_12_013-019_0.pdf (in Russ.)
- Ivanov SYu, Alekseeva NP, Bondarenko BB. Estimation of risk development of paroxysmal atrial fibrillation in patients with coronary artery disease during early postoperative period after coronary artery bypass graft surgery. Vestn SPBU. 2008;11(2):32-36.
https://cyberleninka.ru/article/n/otsenka-riska-vozniknoveniya-paroksizmalnoy-fibrillyatsii-predserdiy-u-bolnyh-ibs-v-rannem-posleoperatsionnom-periode-posle (in Russ.)
- Bokeriia LA. Profilaktika insul’ta pri fibrilliatsii predserdii. Annaly Aritmologii. 2005;(3):47-54. http://arrhythmology.pro/files/pdf/45-54.pdf (in Russ.)
- Heintz KM, Hollenberg SM. Perioperative cardiac issues: postoperative arrhythmias. Surg Clin North Am. 2005 Dec;85(6):1103-14, viii. doi: 10.1016/j.suc.2005.09.003
- Gukov AO, Zhdanov AM. Vozmozhnosti postoiannoi kardiostimuliatsii v profilaktike fibrilliatsii i trepetaniia predserdii. Vestn Aritmologii. 2000;(16):78-84. http://www.vestar.ru/atts/2224/222420.pdf (in Russ.)
- Walsh SR, Tang T, Gaunt ME, Schneider HJ. New arrhythmias after noncardiothoracic surgery. BMJ. 2006 Oct 7;333(7571):715. doi: 10.1136/bmj.333.7571.715
- Auer J, Weber T, Berent R, Ng CK, Lamm G, Eber B. Risk factors of postoperative atrial fibrillation after cardiac surgery. J Card Surg. 2005 Sep-Oct;20(5):425-31. doi: 10.1111/j.1540-8191.2005.2004123.x
- Echahidi N, Pibarot P, O’Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol. 2008 Feb 26;51(8):793-801. doi: 10.1016/j.jacc.2007.10.043
- Yadava M, Hughey AB, Crawford TC. Postoperative atrial fibrillation: incidence, mechanisms, and clinical correlates. Heart Fail Clin. 2016 Apr;12(2):299-308. doi: 10.1016/j.hfc.2015.08.023
- Maesen B, Nijs J, Maessen J, Allessie M, Schotten U. Postoperative atrial fibrillation: a maze of mechanisms. Europace. 2012 Feb;14(2):159-74. Published online 2011 Aug 6. doi: 10.1093/europace/eur208
- Anselmi A, Possati G, Gaudino M. Postoperative inflammatory reaction and atrial fibrillation: simple correlation or causation? Ann Thorac Surg. 2009 Jul;88(1):326-33. doi: 10.1016/j.athoracsur.2009.01.031
- Amar D, Zhang H, Heerdt PM, Park B, Fleisher M, Thaler HT. Statin use is associated with a reduction in atrial fibrillation after noncardiac thoracic surgery independent of C-reactive protein. Chest. 2005 Nov;128(5):3421-27. doi: 10.1378/chest.128.5.3421
- Ho KM, Tan JA. Benefits and risks of corticosteroid prophylaxis in adult cardiac surgery: a dose-response meta-analysis. Circulation. 2009 Apr 14;119(14):1853-66. doi: 10.1161/CIRCULATIONAHA.108.848218
- Olshansky B. Interrelationships between the autonomic nervous system and atrial fibrillation. Prog Cardiovasc Dis. 2005 Jul-Aug;48(1):57-78. doi: 10.1016/j.pcad.2005.06.004
- Villareal RP, Hariharan R, Liu BC, Kar B, Lee VV, Elayda M, Lopez JA, Rasekh A, Wilson JM, Massumi A. Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. J Am Coll Cardiol. 2004 Mar 3;43(5):742-48. doi: 10.1016/j.jacc.2003.11.023
- Hogue CW Jr, Creswell LL, Gutterman DD, Fleisher LA. Epidemiology, mechanisms, and risks: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest. 2005 Aug;128(2 Suppl):9S-16S. doi: 10.1378/chest.128.2_suppl.9S
- Aranki SF, Shaw DP, Adams DH, Rizzo RJ, Couper GS, VanderVliet M, Collins JJ Jr, Cohn LH, Burstin HR. Predictors of atrial fibrillation after coronary artery surgery. Current trends and impact on hospital resources. Circulation. 1996 Aug 1;94(3):390-97. doi: 10.1161/01.CIR.94.3.390
- Almassi GH, Schowalter T, Nicolosi AC, Aggarwal A, Moritz TE, Henderson WG, Tarazi R, Shroyer AL, Sethi GK, Grover FL, Hammermeister KE. Atrial fibrillation after cardiac surgery: a major morbid event? Ann Surg. 1997 Oct;226(4):501-13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1191069/pdf/annsurg00020-0119.pdf
- Ducceschi V, D’Andrea A, Liccardo B, Alfieri A, Sarubbi B, De Feo M, Santangelo L, Cotrufo M. Perioperative clinical predictors of atrial fibrillation occurrence following coronary artery surgery. Eur J Cardiothorac Surg. 1999 Oct;16(4):435-39. doi: 10.1016/s1010-7940(99)00217-1
- Cochrane AD, Siddins M, Rosenfeldt FL, Salamonsen R, McConaghy L, Marasco S, Davis BB. A comparison of amiodarone and digoxin for treatment of supraventricular arrhythmias after cardiac surgery. Eur J Cardiothorac Surg. 1994;8(4):194-98. doi: 10.1016/1010-7940(94)90114-7
- Steinberg JS, Zelenkofske S, Wong SC, Gelernt M, Sciacca R, Menchavez E. Value of the P-wave signal-averaged ECG for predicting atrial fibrillation after cardiac surgery. Circulation. 1993 Dec;88(6):2618-22. doi: 10.1161/01.CIR.88.6.2618
- Archbold RA, Schillings RJ. Atrial pacing for the prevention of atrial fibrillation after coronary artery bypass graft surgery: a review of the literature. Heart. 2004 Feb;90(2):129-33. doi: 10.1136/hrt.2003.015412
- Greenberg MD, Katz NM, Iuliano S, Tempesta BJ, Solomon AJ. Atrial pacing for the prevention of atrial fibrillation after cardiovascular surgery. J Am Coll Cardiol. 2000 May;35(6):1416-22. doi: 10.1016/S0735-1097(00)00610-0
- Levy T, Fotopoulos G, Walker S, Rex S, Octave M, Paul V, Amrani M. Randomized controlled study investigating the effect of biatrial pacing in prevention of atrial fibrillation after coronary artery bypass grafting. Circulation. 2000 Sep 19;102(12):1382-87. doi: 10.1161/01.CIR.102.12.1382
- Gerstenfeld EP, Khoo M, Martin RC, Cook JR, Lancey R, Rofino K, Vander Salm TJ, Mittleman RS. Effectiveness of bi-atrial pacing for reducing atrial fibrillation after coronary artery bypass graft surgery. J Interv Card Electrophysiol. 2001 Sep;5(3):275-83. doi: 10.1067/mhj.2000.105102
- Fan K, Lee KL, Chiu CS, Lee JW, He GW, Cheung D, Sun MP, Lau CP. Effects of biatrial pacing in prevention of postoperative atrial fibrillation after coronary artery bypass surgery. Circulation. 2000 Aug 15;102(7):755-60. doi: 10.1161/01.cir.102.7.755
- Eslami M, Mirkhani HS, Sanatkar M, Bayat H, Sattarzadeh R, Mirhoseini M. Role of biatrial pacing in prevention of atrial fibrillation after coronary artery bypass surgery. Indian Pacing Electrophysiol J. 2005 Jan 1;5(1):5-11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1502073/
- Silva FM, Milani R, Précoma D, Guimarães M, Moutinho JA, Barboza L, Sartori A, Brofman P. Influence of external temporary biatrial pacing on the prevention of atrial fibrillation after coronary artery bypass without extracorporeal circulation. Arq Bras Cardiol. 2008 Feb;90(2):80-85. https://www.ncbi.nlm.nih.gov/m/pubmed/18392378 [Article in English, Portuguese]
- Arsenault KA, Yusuf AM, Crystal E, Healey JS, Morillo CA, Nair GM, Whitlock RP. Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD003611. doi: 10.1002/14651858.CD003611.pub3
- Rubaj A, Rucinski P, Kutarski A, Dabrowska-Kugacka A, Oleszczak K, Zimon B, Trojnar M, Zapolski T, Drozd J, Tarkowski A, Wysokinski A. Cardiac hemodynamics and proinflammatory cytokines during biatrial and right atrial appendage pacing in patients with interatrial block. J Interv Card Electrophysiol. 2013 Aug;37(2):147-54. doi: 10.1007/s10840-013-9792-8
- Maisel WH., Epstein AE. The role of cardiac pacing: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest. 2005;128(2 Suppl):36S-38S. doi: 10.1378/chest.128.2_suppl.36S
- Andrews TC, Reimold SC, Berlin JA, Antman EM. Prevention of supraventricular arrhythmias after coronary artery bypass surgery. A meta-analysis of randomized control trials. Circulation. 1991 Nov;84(5 Suppl):III236-44. https://www.ncbi.nlm.nih.gov/pubmed/1682069
- Fuster V, Rydå?n LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, Halperin JL, Le Heuzey YV, Kay GN, Lowe JE, Olsson SB, Prystowsky EN, Tamargo JL, Wann S, Smith Jr SC, Jacobs AK, Adams CD, Anderson JL, Antman EM, Hunt SA, Nishimura R, Ornato JP, Page RL, Riegel B, Priori SG, Blanc JJ, Budaj A, Camm AJ, Dean V, Deckers JW, Despres C, Dickstein K, Lekakis J, McGregor K, Metra M, Morais J, Osterspey A, Tamargo JL, Zamorano JL. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: full text: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 guidelines for the management of patients with atrial fibrillation) developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation 2006;114:e257-e354. doi: 10.1161/CIRCULATIONAHA.106.177292
- Bessissow A, Khan J, Devereaux P, Alvarez-Garcia J, Alonso-Coello P. Postoperative atrial fibrillation in non-cardiac and cardiac surgery: an overview. J Thromb Haemost. 2015 Jun;13(Suppl 1):S304-12. doi: 10.1111/jth.12974
- Akbarzadeh F, Kazemi-Arbat B, Golmohammadi A, Pourafkari L. Biatrial pacing vs. intravenous amiodarone in prevention of atrial fibrillation after coronary artery bypass surgery. Pak J Biol Sci. 2009 Oct 1;12(19):1325-29. doi: 10.3923/pjbs.2009.1325.1329
- Mitchell LB, Exner DV, Wyse DG, Connolly CJ, Prystai GD, Bayes AJ, Kidd WT, Kieser T, Burgess JJ, Ferland A, MacAdams CL, Maitland A. Prophylactic oral amiodarone for the prevention of arrhythmias that begin early after revascularization, valve replacement, or repair: PAPABEAR: a randomized controlled trial. JAMA. 2005 Dec 28;294(24):3093-100. doi: 10.1001/jama.294.24.3093
- Weber UK, Osswald S, Huber M, Buser P, Skarvan K, Stulz P, Schmidhauser C, Pfisterer M. Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification?: A prospective placebo-controlled study using low-dose sotalol. Eur Heart J. 1998 May 1;19(5):794-800. doi: 10.1053/euhj.1997.0838
- Pfisterer ME, Klöter-Weber UC, Huber M, Osswald S, Buser PT, Skarvan K, Stulz PM. Prevention of supraventricular tachyarrhythmias after open heart operation by low-dose sotalol: a prospective, double-blind, randomized, placebo-controlled study. Ann Thorac Surg. 1997 Oct;64(4):1113-19. doi: 10.1016/s0003-4975(97)00804-7
- Gomes JA, Ip J, Santoni-Rugiu F, Mehta D, Ergin A, Lansman S, Pe E, Newhouse TT, Chao S. Oral d,l sotalol reduces the incidence of postoperative atrial fibrillation in coronary artery bypass surgery patients: a randomized, double-blind, placebo-controlled study. J Am Coll Cardiol. 1999 Aug;34(2):334-39. doi: 10.1016/S0735-1097(99)00213-2
- Serafimovski N, Burke P, Khawaja O, Sekulic M, Machado C. Usefulness of dofetilide for the prevention of atrial tachyarrhythmias (atrial fibrillation or flutter) after coronary artery bypass grafting. Am J Cardiol. 2008 Jun 1;101(11):1574-79. doi: 10.1016/j.amjcard.2008.01.044
- Levy T, Fotopoulos G, Walker S, Rex S, Octave M, Paul V, Amrani M. Randomized controlled study investigating the effect of biatrial pacing in prevention of atrial fibrillation after coronary artery bypass grafting. Circulation. 2000 Sep 19;102(12):1382-87. doi: 10.1161/01.cir.102.12.1382
- Zangrillo A, Landoni G, Sparicio D, Pappalardo F, Bove T, Cerchierini E, Sottocorna O, Aletti G, Crescenzi G. Perioperative magnesium supplementation to prevent atrial fibrillation after off-pump coronary artery surgery: a randomized controlled study. J Cardiothorac Vasc Anesth. 2005 Dec;19(6):723-28. doi: 10.1053/j.jvca.2005.02.015
- Bokeriia OL, Akhobekov AA, Shvarts VA, Kudzoeva ZF. Efficacy of statin therapy in the prevention of atrial fibrillation in early postoperative period after coronary artery bypass grafting. Vestn RAMN. 2015;70(3):273–78. doi: 10.15690/vramn.v70i3.1322 (in Russ.)
121552, Russian Federation,
Moscow, Rublevskoye Highway, 135,
A.N. Bakulev National Medical Research
Center of Cardiovascular Surgery,
Department of Surgical Treatment
Of Interactive Pathology,
Tel.: +7 929 647 10 75,
Furkatdzon S. Gafurov
Bockeria Leo A., MD, Academician of RAS, Director of A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow, Russian Federation.
Bockeria Olga L, MD, Corresponding Member of RAS, Chief Researcher, Department of Surgical Treatment of Interactive Pathology, A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow, Russian Federation.
Gafurov Furkatdzon S., Post-Graduate Student, Department of Surgical Treatment of Interactive Pathology, A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow, Russian Federation.
V.V. HOMOCHKIN, S.S. MASKIN, N.V. HOMOCHKINA, V.V. EROFITSKAYA
LIGATION OF THE INTERSPHINCTERIC FISTULA TRACT IN TREATMENT OF CHRONIC PARAPROCTITIS
Volgograd State Medical University, Volgograd,
The Russian Federation
In the review, a comparative analysis of the use of traditional techniques and organ-preserving ligation of intersphincteric fistula tract (LIFT) in the treatment of chronic paraproctitis was carried out. The use of traditional methods is effective in 60-80% of cases; nevertheless, the risk of anal incontinence formation is, on average, 28%. The ligation of the intersphincteric fistula tract (LIFT) allows achieving convalescence in 82 - 95% of cases, and besides the majority of specialists emphasizes almost complete absence of disturbance of anal competence. In the vast majority of cases, recurrence of the postoperative fistula is formed as intersphincteric type that allows eliminating it without any risk of incontinence. In rare cases of «complete» recurrent fistula formation there is a possibility to perform sphincter-preserving operation. In patients with initially recurrent fistulas, the percentage of recovery is 90% and more. While comparing the classical operation LIFT and LIFT-plus (with the removal of distal part of fistula), the efficiency of LIFT- plus is higher by an average of 4-5%.
The performed analysis proves the advantages of the sphincter-saving operation LIFT in comparison with the classical methods of elimination of the pararectal fistulas. The problem of combining the LIFT with other procedures remains unsolved and demands further investigations.
- Bogormistrov IS, Frolov SA, Kuzminov AM, Borodkin AS, Korolik VYu, Minbayev ShT. Surgical methods of treatment of extrasphincter and transsphincteric fistulas of the rectum (literature review). Ros Zhurn Gastroenterologii Gepatologii Koloproktologii. 2015;25(4):92-100. http://www.gastroj.ru/files/_4_2015_s14_1447885430.pdf (in Russ.)
- Grishin KN, Mustafin DG, Esin VI. Sravnitel’naia otsenka rezul’tatov razlichnykh sposobov khirurgicheskogo lecheniia ekstrasfinkternykh svishchei priamoi kishki. Koloproktologiia. 2009;29(3):4-8. http://www.gnck.ru/pdf/Content_3_29_2009.pdf (in Russ.)
- Madaminov ÀÌ, Bektenov YÀ, Aysaev AYu, Lyukhurov RN. The method of surgical treatment transsphincteric and extrasphincteric fistula of the rectum. Vestn KRSU. 2015;15(7):99-101. https://www.krsu.edu.kg/vestnik/2015/v7/a28.pdf (in Russ.)
- Ektov VN, Popov RV, Vollis EA. Sovremennye podkhody k vyboru khirurgicheskoi taktiki v lechenii bol‘nykh priamokishechnymi svishchami. Koloproktologiia. 2014;49(3):62-69. http://www.gnck.ru/pdf/journal_3_49_2014.pdf (in Russ.)
- Krasnova VN, Chernov AA, Katorkin SE, Zhuravlev AV. Comparative results of the experience in the ligation of intersphinteric fistula tract in the treatment of transsphincteric and extrasphincteric anal fistulas. Vrach-Aspirant. 2017;80(1.1):179-189. https://elibrary.ru/item.asp?id=28114148 (in Russ.)
- Titov AIu, Kostarev IV, Anosov IS, Fomenko OIu. Pervyi opyt pereviazki svishchevogo khoda v mezhsfinkternom prostranstve (LIFT-metodika) v lechenii patsientov s trans – i ekstrasfinkternymi svishchami priamoi kishki. Koloproktologiia. 2016;58(4):47-53. http://www.gnck.ru/pdf/journal_4_58_2016.pdf (in Russ.)
- Sileri P, Franceschilli L, Angelucci GP, D’Ugo S, Milito G, Cadeddu F, Selvaggio I, Lazzaros S, Gaspari AL. Ligation of the intersphincteric fistula tract (LIFT) to treat anal fistula: early results from a prospective observational study. Tech Coloproctol. 2011 Dec;15(4):413-6. doi: 10.1007/s10151-011-0779-0
- Hong KD, Kang S, Kalaskar S, Wexner SD. Ligation of intersphincteric fistula tract (LIFT) to treat anal fistula: systematic review and meta-analysis. Tech Coloproctol. 2014 Aug;18(8):685-91. doi: 10.1007/s10151-014-1183-3
- Han JG, Wang ZJ, Zheng Y, Chen CW, Wang XQ, Che XM, Song WL, Cui JJ. Ligation of intersphincteric fistula tract vs ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug procedure in patients with transsphincteric anal fistula: early results of a multicenter prospective randomized trial. Ann Surg. 2016 Dec;264(6):917-22. doi: 10.1097/SLA.0000000000001562
- Lengyel AJ, Hurst NG, Williams JG. Pre-operative assessment of anal fistulas using endoanal ultrasound. Colorectal Dis. 2002 Nov;4(6):436-40. doi: 10.1046/j.14631318.2002.00377.x
- Parks AG, Gordon PH, Hardcastle JD. A classification of fistula-in-ano. Br J Surg. 1976 Jan;63(1):1-12. doi: 10.1002/bjs.1800630102
- Sheshaberidze MS. Operativnoe lechenie slozhnykh ekstrasfinkternykh i transsfinkternykh svishchei priamoi kishki. Khirurgiia. Zhurn im NI Pirogova. 2001;(10):43-46. http://www.lib.krsu.edu.kg/uploads/files/public/2108.pdf (in Russ.)
- Vergara-Fernandez O, Espino-Urbina LA. Ligation of intersphincteric fistula tract: What is the evidence in a review? World J Gastroenterol. 2013 Oct 28;19(40):6805-13. doi: 10.3748/wjg.v19.i40.6805
- Ommer A, Wenger FA, Rolfs T, Walz MK. Continence disorders after anal surgery – a relevant problem? Int J Colorectal Dis. 2008 Nov;23(11):1023-31. doi: 10.1007/s00384-008-0524-y
- Subhas G, Singh Bhullar J, Al-Omari A, Unawane A, Mittal VK, Pearlman R. Setons in the treatment of anal fistula: review of variations in materials and techniques. Dig Surg. 2012;29(4):292-300. doi: 10.1159/000342398
- Rosen DR, Kaiser AM. Definitive seton management for transsphincteric fistula-in-ano: harm or charm? Colorectal Dis. 2016 May;18(5):488-95. doi: 10.1111/codi.13120
- Vial M, Parés D, Pera M, Grande L. Faecal incontinence after seton treatment for anal fistulae with and without surgical division of internal anal sphincter: a systematic review. Colorectal Dis. 2010 Mar;12(3):172-8. doi: 10.1111/j.1463-1318.2009.01810.x
- Ritchie RD, Sackier JM, Hodde JP. Incontinence rates after cutting seton treatment for anal fistula. Colorectal Dis. 2009 Jul;11(6):564-71. doi: 10.1111/j.1463-1318.2008.01713.x
- Patton V, Chen CM, Lubowski D. Long-term results of the cutting seton for high anal fistula. ANZ J Surg. 2015 Oct;85(10):720-7. doi: 10.1111/ans.13156
- Lykke A, Steendahl J, Wille-Jørgensen PA. Treating high anal fistulae with slow cutting seton. Ugeskr Laeger. 2010 Feb 15;172(7):516-19. https://www.ncbi.nlm.nih.gov/pubmed/20156398 [Article in Danish]
- Durgun V, Perek A, Kapan M, Kapan S, Perek S. Partial fistulotomy and modified cutting seton procedure in the treatment of high extrasphincteric perianal fistulae. Dig Surg. 2002;19(1):56-58. doi: 10.1159/000052007
- Göttgens KW, Janssen PT, Heemskerk J, van Dielen FM, Konsten JL, Lettinga T, Hoofwijk AG, Belgers HJ, Stassen LP, Breukink SO. Long-term outcome of low perianal fistulas treated by fistulotomy: a multicenter study. Int J Colorectal Dis. 2015 Feb;30(2):213-19. doi: 10.1007/s00384-014-2072-y
- Arroyo A, Pérez-Legaz J, Moya P, Armañanzas L, Lacueva J, Pérez-Vicente F, Candela F, Calpena R. Fistulotomy and sphincter reconstruction in the treatment of complex fistula-in-ano: long-term clinical and manometric results. Ann Surg. 2012 May;255(5):935-39. doi: 10.1097/SLA.0b013e31824e9112
- Ortiz H, Marzo M, de Miguel M, Ciga MA, Oteiza F, Armendariz P. Length of follow-up after fistulotomy and fistulectomy associated with endorectal advancement flap repair for fistula in ano. Br J Surg. 2008 Apr;95(4):484-87. doi: 10.1002/bjs.6023
- Christiansen J, Rønholt C. Treatment of recurrent high anal fistula by total excision and primary sphincter reconstruction. Int J Colorectal Dis. 1995;10(4):207-9. https://link.springer.com/article/10.1007/BF00346220
- Zirak-Schmidt S, Perdawood SK. Management of anal fistula by ligation of the intersphincteric fistula tract – a systematic review. Dan Med J. 2014 Dec;61(12):A4977. https://www.ncbi.nlm.nih.gov/pubmed/25441733
- Alasari S, Kim NK. Overview of anal fistula and systematic review of ligation of the intersphincteric fistula tract (LIFT). Tech Coloproctol. 2014 Jan;18(1):13-22. doi: 10.1007/s10151-013-1050-7
- Rojanasakul A, Pattanaarun J, Sahakitrungruang C, Tantiphlachiva K. Total anal sphincter saving technique for fistula-in-ano; the ligation of intersphincteric fistula tract. J Med Assoc Thai. 2007 Mar;90(3):581-86. https://pdfs.semanticscholar.org/67b1/cafa96b98a8287df29e5de33cf449541cdee.pdf
- Tan KK, Tan IJ, Lim FS, Koh DC, Tsang CB. The anatomy of failures following the ligation of intersphincteric tract technique for anal fistula: a review of 93 patients over 4 years. Dis Colon Rectum. 2011 Nov;54(11):1368-72. doi: 10.1097/DCR.0b013e31822bb55e
- Bleier JI, Moloo H, Goldberg SM. Ligation of the intersphincteric fistula tract: an effective new technique for complex fistulas. Dis Colon Rectum. 2010 Jan;53(1):43-46. doi: 10.1007/DCR.0b013e3181bb869f
- Sirikurnpiboon S, Awapittaya B, Jivapaisarnpong P. Ligation of intersphincteric fistula tract and its modification: Results from treatment of complex fistula. World J Gastrointest Surg. 2013 Apr 27;5(4):123-28. doi: 10.4240/wjgs.v5.i4.123
- Wu W, Yang G, Du Z, Zhang X, Song Y, Qiu J, Liao X, Shen Z. Modified ligation of the intersphincteric fistula tract in the treatment of simple transsphincteric perianal fistula. Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Dec;17(12):1194-97. https://www.ncbi.nlm.nih.gov/pubmed/25529951 [Article in Chinese]
- Ye F, Tang C, Wang D, Zheng S. Early experience with the modificated approach of ligation of the intersphincteric fistula tract for high transsphincteric fistula. World J Surg. 2015 Apr;39(4):1059-65. doi: 10.1007/s00268-014-2888-1
- Abcarian AM, Estrada JJ, Park J, Corning C, Chaudhry V, Cintron J, Prasad L, Abcarian H. Ligation of intersphincteric fistula tract: early results of a pilot study. Dis Colon Rectum. 2012 Jul;55(7):778-82. doi: 10.1097/DCR.0b013e318255ae8a
- Van Onkelen RS, Gosselink MP, Schouten WR. Ligation of the intersphincteric fistula tract in low transsphincteric fistulae: a new technique to avoid fistulotomy. Colorectal Dis. 2013 May;15(5):587-91. doi: 10.1111/codi.12030
- Shanwani A, Nor AM, Amri N. Ligation of the intersphincteric fistula tract (LIFT): a sphincter-saving technique for fistula-in-ano. Dis Colon Rectum. 2010 Jan;53(1):39-42. doi: 10.1007/DCR.0b013e3181c160c4
- Parthasarathi R, Gomes RM, Rajapandian S, Sathiamurthy R, Praveenraj P, Senthilnathan P, Palanivelu C. Ligation of the intersphincteric fistula tract for the treatment of fistula-in-ano: experience of a tertiary care centre in South India. Colorectal Dis. 2016 May;18(5):496-502. doi: 10.1111/codi.13162
- Chen H, Gu Y, Sun G, Zhou Z, Zhu P, Wu S, Yang B. Ligation of intersphincteric fistula tract in the treatment of complicated fistula-in-ano. Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Dec;17(12):1190-93. https://www.ncbi.nlm.nih.gov/pubmed/25529950 [Article in Chinese]
- Chen HJ, Sun GD, Zhu P, Zhou ZL, Chen YG, Yang BL. Effective and longterm outcome following ligation of the intersphincteric fistula tract (LIFT) for transsphincteric fistula. Int J Colorectal Dis. 2017 Apr;32(4):583-85. doi: 10.1007/s00384-016-2723-2
- Sirany AM, Nygaard RM, Morken JJ. The ligation of the intersphincteric fistula tract procedure for anal fistula: a mixed bag of results. Dis Colon Rectum. 2015 Jun;58(6):604-12. doi: 10.1097/DCR.0000000000000374
- Tian Y, Zhang Z, An S, Jia S, Liu L, Yu H. Clinical observation of the ligation of intersphincteric fistula tract in the treatment of simple anal fistula. Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Dec;18(12):1211-14. https://m.eurekamag.com/research/057/423/057423863.php [Article in Chinese]
- Araújo SEA, Marcante MT, Mendes CRS, Bertoncini AB, Seid VE, Horcel LA, Perez RO, Klajner S. Interesfincterial ligation of fistula tract (LIFT) for patients with anal fistulas: a Brazilian BI-Institutional experience. Arq Bras Cir Dig. 2017 Oct-Dec;30(4):235-38. doi: 10.1590/0102-6720201700040002 [Article in English, Portuguese]
- Campbell ML, Abboud EC, Dolberg ME, Sanchez JE, Marcet JE, Rasheid SH. Treatment of refractory perianal fistulas with ligation of the intersphincteric fistula tract: preliminary results. Am Surg. 2013 Jul;79(7):723-27. https://www.ingentaconnect.com/contentone/sesc/tas/2013/00000079/00000007/art00018
- Chekanov MN, Chekanov AM. Otdalennye rezul’taty ligirovaniia svishchei priamoi kishki v mezhsfinkternom sloe. Meditsina i obrazovanie v Sibiri [Elektronnyi resurs]. 2014;(5). 5 s. [Data dostupa: 18.05.2017]. Rezhim dostupa: http://www.ngmu.ru/cozo/mos/article/text_full.php?id=1545 (in Russ.)
- Romaniszyn M, Walega PJ, Nowak W. Efficacy of lift (ligation of intersphincteric fistula tract) for complex and recurrent anal fistulas – a single-center experience and a review of the literature. Pol Przegl Chir. 2015 Feb 3;86(11):532-36. doi: 10.2478/pjs-2014-0094
- van Onkelen RS, Gosselink MP, Schouten WR. Is it possible to improve the outcome of transanal advancement flap repair for high transsphincteric fistulas by additional ligation of the intersphincteric fistula tract? Dis Colon Rectum. 2012 Feb;55(2):163-66. doi: 10.1097/DCR.0b013e31823c0f74
- Ellis CN. Outcomes with the use of bioprosthetic grafts to reinforce the ligation of the intersphincteric fistula tract (BioLIFT procedure) for the management of complex anal fistulas. Dis Colon Rectum. 2010 Oct;53(10):1361-64. doi: 10.1007/DCR.0b013e3181ec4470
- Bleier L, Moloo H. Current management of cryptoglandular fistula-in-ano. World J Gastroenterol. 2011 Jul 28;17(28):3286-91. doi: 10.3748/wjg.v17.i28.3286
400131, Russian Federation,
Volgograd, Pavshikh Bortsov Sq., 1,
Volgograd State Medical University,
Depatrment of Surgical Diseases
Tel.: +7 988 490 75 00,
Vitaliy V. Homochkin
Homochkin Vitaliy V., PhD, Associate Professor of the Department of Surgical Diseases and Neurosurgery of the Faculty of Advanced Training of Physicians, Volgograd State Medical University, Volgograd, Russian Federation.
Maskin Sergey S., MD, Professor, Head of the Department of Hospital Surgery, Volgograd State Medical University, Volgograd, Russian Federation.
Homochkina Nataliya V., Clinical Intern of the Department of Surgical Diseases and Neurosurgery of the Faculty of Advanced Training of Physicians, Volgograd State Medical University, Volgograd, Russian Federation.
Erofitskaya Victoria V., Assistant of the Department of Hospital Surgery, Volgograd State Medical University, Volgograd, Russian Federation.
K.I. SERGATSKIY, V.I. NIKOLSKIY, V.A. SIZOVA, V.V. PETROVA
CLINICAL OBSERVATIONS OF RARE COMPLICATION OF VAGINAL CANCER IN THE FORM OF PARARECTAL CELL AND SOFT TISSUE PHLEGMON OF ADJACENT ANATOMICAL AREAS
Penza State University, Penza,
The Russian Federation
Vaginal cancer is a relatively rare neoplasm, and this pathology is 1-3% of the total number of female genitalia tumors. The incidence of vaginal cancer is 1 per 100,000 women. The peak incidence of vaginal cancer falls on the 6th and 7th life decade. This tumor is detected in less than 15% of patients before 50 years old, and less than 10% of cases occur before 40 years. Almost 90% of all histological types of malignant vaginal tumors occur in squamous cell carcinoma. The most frequent complications of vaginal cancer are the following: bleeding from the tumor, fistula, ulceration and urethral compression. Two cases of vaginal cancer complications by pararectal and soft tissue phlegmon of adjacent anatomical areas was identified in clinical practice. Phlegmon of pararectal tissue and perineum of non-cryptogenic genesis is often observed in the decay and abscessing of rectum malignant neoplasms. The complication of primary vaginal cancer in the form of soft tissue phlegmon in our clinical practice has been seen for the first time. There are no descriptions of such clinical cases in the available literature. Treatment of patients with vaginal malignant tumors complicated by phlegmon of the soft tissues has shown a satisfactory clinical result.
- Gritsai AA, Korzhevskaia EV, Kravets OA, Kuznetsov VV, Khokhlova SV. Klinicheskie rekomendatsii po diagnostike i lecheniiu bol’nykh rakom vlagalishcha. Moscow, RF; 2014. 11 p. http://www.oncology.ru/association/clinical-guidelines/2014/05.pdf (in Russ.)
- Bokhman IaV. Rukovodstvo po onkoginekologii. Leningrad, SSSR: Meditsina; 1989. 464 p. http://med-books.by/onkologiya/3463-rukovodstvo-po-onkoginekologii-bohman-yav-1989-god-464-s.html (in Russ.)
- Vorob’eva LI, Nespriad’koSV, Goncharuk IV, Bakai OA, Ganich AV. Rak vlagalishcha: sovremennoe sostoianie. Klin Onkologiia. 2014;1(13):46-50. http://nbuv.gov.ua/UJRN/klinonk_2014_1_12. (in Russ.)
- Davydov MI, Kuznetsov VV. Lektsii po onkoginekologii. Moscow, RF: MEDpressinform. 2009. 432 p.
http://www.03book.ru/upload/iblock/1ac/331_Lekcii_po_onkoginekologiibKuznecovq.pdf (in Russ.)
- Kulakov VI, Selezneva ND, Beloglazova SE. Rukovodstvo po operativnoi ginekologii. Moscow, RF: Medinform Agentst vo; 2006. 639 p. https://www.ozon.ru/context/detail/id/3712527/ (in Russ.)
- Abe K, Kameyama H, Shimada Y, Yamada S, Soma D, Yagi R, Miura K, Tatsuda K, Tajima Y, Okamura T, Nakano M, Nakano M, Kobayashi T, Kosugi S, Wakai T. A case of rectal carcinoma with recurrence around the drainage site complicated by Fournier’s gangrene. Gan To Kagaku Ryoho. 2015 Nov;42(12):2291-93. http://europepmc.org/abstract/med/26805341 [Article in Japanese]
- Hamidian Jahromi A, DuBose A, Skweres J, Johnson L, Cole P. Oncologic management dilemma of locally advanced occult rectal cancer presenting as Fournier’s gangrene. Am Surg. 2015 Apr;81(4):E184-87. https://www.highbeam.com/doc/1P3-3658065281.html
- Koyama M, Kitazawa M, Ehara T, Yamamoto Y, Suzuki A, Miyagawa Y, Miyagawa S. Two cases of fournier’s gangrene that occurred during chemotherapy for rectal cancer. Gan To Kagaku Ryoho. 2017 Feb;44(2):169-71. https://www.ncbi.nlm.nih.gov/pubmed/28223677 [Article in Japanese]
440026, Russian Federation,
Penza, Krasnaya Str., 40,
Penza State University,
Department of Surgery,
Tel. mobile: 8 902 354-04-68,
Konstantin I. Sergatskiy
Sergatskiy Konstantin I., PhD, Associate Professor of the Department of Surgery, medical university, Penza State University, Penza, Russian Federation.
Nikolsky Valery I., MD, Professor of the Department of Surgery, medical university, Penza State University, Penza, Russian Federation.
Sizova Vasilisa A., 5-Year Student, medical university, Penza State University, Penza, Russian Federation.
Petrova Victoriya V., 5-Year Student, medical university, Penza State University, Penza, Russian Federation.
I.V. RESHETOV, I.I. BYKOV, A.A. SHEVALGIN, YU.S. KUROCHKINA, T.P. NEKRASOVA, M.S. MIKEROVA
SYNCHRONOUS PRIMARY-MULTIPLE MALIGNANT TUMOR: BIFENOTYPIC SYNONASAL SARCOMA AND COLORECTAL CANCER
I.M. Sechenov First Moscow State Medical University, Moscow,
The Russian Federation
Primary-multifocal malignant tumors hold a specific place in oncology. Present case report describes the combination of two neoplastic processes with different anatomic localization, the analogues to which have not been found either in the domestic literature or foreign sources.
The article presents the case of a synchronous primary-multiple malignant neoplasm – malignant tumor from the membranes of the peripheral nerves of the nasal cavity with expansion into the right maxillary sinus, the cells of the ethmoidal sinus Ò2bN0M0 and moderately differentiated adenocarcinoma of the sigmoid colon Ò4àN0M0. Physical examination and positron emission tomography combined with the computed tomography confirmed a hypervascular tumor of the posterior cells of the ethmoidal sinus and a nasal cavity without hypermetabolism and the circular tumor of the sigmoid colon with hypermetabolism. Taking into account the primary-multiple character of the lesion and the clinic of intestinal obstruction, a tactic of the treatment was a combined surgery – the removal of the neoplasm of the nasal cavity with resection of the right maxillary sinus with microsurgical technique and a reconstructive-plastic component using a coronary access, laparotomy, resection of the sigmoid colon, lymphadenectomy. The chosen treatment allowed eliminating both of the tumors in a short time and moving on to a further stage of treatment. The patient is under the supervision, there is no recurrence of the disease at the moment.
- Chissov VI, Starinskii VV, Petrova GV, red. Zlokachestvennye novoobrazovaniia v Rossii v 2011 g. (zabolevaemost’ i smertnost’). Moscow, RF: MNIOI im PA Gertsena; 2013. 289 p. http://www.oncology.ru/service/statistics/malignant_tumors/2011.pdf (in Russ.)
- Wong WJ, Lauria A, Hornick JL, Xiao S, Fletcher JA, Marino-Enriquez A. Alternate PAX3-FOXO1 oncogenic fusion in biphenotypic sinonasal sarcoma. Genes Chromosomes Cancer. 2016 Jan;55(1):25-29. doi: 10.1002/gcc.22295
- Huang SC, Ghossein RA, Bishop JA, Zhang L, Chen TC, Huang HY, Antonescu CR. Novel PAX3-NCOA1 fusions in biphenotypic sinonasal sarcoma with focal rhabdomyoblastic differentiation. Am J Surg Pathol. 2016 Jan;40(1):51-59. doi: 10.1097/PAS.0000000000000492
- Wang X, Bledsoe KL, Graham RP, Asmann YW, Viswanatha DS, Lewis JE, Lewis JT, Chou MM, Yaszemski MJ, Jen J, Westendorf JJ, Oliveira AM. Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. Nat Genet. 2014 Jul;46(7):666-68. doi: 10.1038/ng.2989
- Rooper LM, Huang SC, Antonescu CR, Westra WH, Bishop JA. Biphenotypic sinonasal sarcoma: an expanded immunoprofile including consistent nuclear β-catenin positivity and absence of SOX10 expression. Hum Pathol. 2016 Sep;55:44-50. doi: 10.1016/j.humpath.2016.04.009
- Fritchie KJ, Jin L, Wang X, Graham RP, Torbenson MS, Lewis JE, Rivera M, Garcia JJ, Schembri-Wismayer DJ, Westendorf JJ, Chou MM, Dong J, Oliveira AM. Fusion gene profile of biphenotypic sinonasal sarcoma: an analysis of 44 cases. Histopatho-logy. 2016 Dec;69(6):930-36. doi: 10.1111/his.13045
- Lin Y, Liao B, Han A. Biphenotypic sinonasal sarcoma with diffuse infiltration and intracranial extension: a case report. Int J Clin Exp Pathol. 2017; 10(12):11743-46. http://www.ijcep.com/files/ijcep0062441.pdf
- Cannon RB, Wiggins RH 3rd, Witt BL, Dundar Y, Johnston TM, Hunt JP. Imaging and outcomes for a new entity: low-grade sinonasal sarcoma with neural and myogenic features. J Neurol Surg Rep. 2017 Jan;78(1):e15-e19. doi: 10.1055/s-0037-1598198
- Lewis JT, Oliveira AM, Nascimento AG, Schembri-Wismayer D, Moore EA, Olsen KD, Garcia JG, Lonzo ML, Lewis JE. Low-grade sinonasal sarcoma with neural and myogenic features: a clinicopathologic analysis of 28 cases. Am J Surg Pathol. 2012 Apr;36(4):517-25. doi: 10.1097/PAS.0b013e3182426886
- Haraldsdottir S, Einarsdottir HM, Smaradottir A, Gunnlaugsson A, Halfdanarson TR. Colorectal cancer – review. Laeknabladid. 2014 Feb;100(2):75-82. http://europepmc.org/abstract/MED/24639430ED/24639430 [Article in Icelandic]
119991, Russian Federation,
Moscow, Trubetskaya str., 8-2,
I.M. Sechenov First Moscow
State Medical University,
Department of Public Health
And Healthcare Named after N.A. Semashko,
Tel. +7 915 225 86 89,
Maria S. Mikerova
Reshetov Igor V., MD, Academician of RAS, Professor, Head of the Department of Oncology and Reconstructive Surgery, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Bykov Igor I., PhD, Oncologist, Oncologic Surgery Unit of Combined Treatment Methods, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Shevalgin Alexandr A., Oncologist, Oncologic Surgery Unit of Combined Treatment Methods, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Kurochkina Juliya S., Oncologist, Oncologic Surgery Unit of Combined Treatment Methods, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Nekrasova Tatiyana P., PhD, Associate Professor of the Department of Pathological Anatomy named after Academician A.I. Strukov, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Mikerova Maria S., PhD, Associate Professor of the Department of Public Health and Healthcare named after N.A. Semashko, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.