Year 2015 Vol. 23 No 2

GENERAL AND SPECIAL SURGERY

E.Y. SOLDATSKY, S.M. YUMIN, A.V. ANDRIYASHKIN, I.A. ZOLOTUKHIN, A.I. KIRIENKO

COMPARISON OF THE LONG -TERM OUTCOMES OF FEMOROPOPLITEAL DEEP VENOUS THROMBOSIS

Russian National Research Medical University named after N.I. Pirogov, Moscow,
The Russian Federation

Objectives. To study the long-term outcomes of femoropopliteal deep venous thrombosis and to compare them with the clinical results after an isolated distal deep vein thrombosis.
Methods. The case-control study with a pair design has been carried out. 88 patients were enrolled in the study treated for deep venous thrombosis (DVT) of the femoropopliteal (the main group, n=44) and distal segments (the control group, n=44). Patients examination included anamnesis taking, physical examination, analysis of available medical records, questioning using questionnaire CIVIQ2 (the quality of life), ultrasound angioscanning of the veins.
Results. According to the incidence of risk factors detection such as trauma, oncological diseases, congenital thrombophilia, air flight, hormonal drugs, no statistically significant differences were found (p>0,05). Overweight was frequently detected in the main group (p=0,039). In the control group the number of patients subjected DVT shortly prior surgery (p=0,039) was 2-fold higher.
The recurrence rate (the same 2-fold higher) in the study group was 9% (p=0,398). There were 14 cases (32%) of pulmonary embolism in the main group and 4 cases (9%) in the control group (p=0,0021). Commitment to treatment was higher in patients of the main group. The incidence of chronic venous insufficiency (classes C3-C6 by CEAP) in the main group was 73% and 17% - in the control group (p=0,001). An additional evaluation criterion was index of venous disease severity by VCSS scale. Its average values was 4,6% in the main group and 3,3% in the control group (p=0,004). The differences were statistically significant. The groups didnt differ statistically according to the level of life quality.
Conclusion. Venous thrombosis of femoropopliteal localization according to its clinical outcomes differs from distal deep vein thrombosis and leads to more expressed manifestation of post-thrombotic diseases. From the point of life quality there are no differences between the femoropopliteal and distal deep vein thrombosis.

Keywords: chronic venous insufficiency, distal deep venous thrombosis, treatment, post-thrombotic syndrome, long-term outcomes, evaluation criteria, life quality
p. 176-181 of the original issue
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Address for correspondence:
117049, Rossiyskaya Federatsiya,
g. Moskva, Leninskiy prospekt d. 10, korp. 5,
"Rossiyskiy natsionalnyiy issledovatelskiy meditsinskiy universitet
im. N.I. Pirogova", kafedra fakultetskoy khirurgii 1,
tel. office: 7-910-474-95-11,
e-mail: netbobr@bk.ru,
Soldatsky Evgeniy Yurevich
Information about the authors:
Soldatsky E.Y. A post-graduate student of the faculty surgery chair N1 of the medical faculty of Russian National Research Medical University named after N.I. Pirogov.
Yumin S.M. PhD, an assistant of the faculty surgery chair N1 of the medical faculty of Russian National Research Medical University named after N.I. Pirogov.
Andriyashkin A.V. PhD, an associate professor of the faculty surgery chair N1 of the medical faculty of Russian National Research Medical University named after N.I. Pirogov.
Zolotukhin I.A. MD, professor of the faculty surgery chair1 of the medical faculty of Russian National Research Medical University named after N.I. Pirogov.
Kirienko A.I. MD, professor, Academician of RAMS, a head of the faculty surgery chair N1 of the medical faculty of Russian National Research Medical University named after N.I. Pirogov.
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